Publications by authors named "Ajar N Yadav"

Article Synopsis
  • Artificial intelligence (AI) combines machine learning and deep learning, playing a vital role in medicine by predicting drug behavior and enhancing healthcare services, leading to better clinical outcomes and cost savings.* -
  • Recent advancements in biomedical research have created a demand for new technologies, workforce, and standards, paving the way for a healthcare revolution through the integration of AI and health data.* -
  • The review highlights AI technologies that can expedite drug development, improve product quality, and ensure safety during manufacturing, especially by predicting the structure of target proteins.*
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Nitrogen, phosphorus, and potassium are the three most essential micronutrients which play major roles in plant survivability by being a structural or non-structural component of the cell. Plants acquire these nutrients from soil in the fixed (NO, NH) and solubilized forms (K, HPO and HPO). In soil, the fixed and solubilized forms of nutrients are unavailable or available in bare minimum amounts; therefore, agrochemicals were introduced.

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  • The study examines the presence of endophytic fungi in nettle leaves and their antibacterial and antioxidant properties.
  • Researchers observed extensive fungal growth throughout the leaves, isolating 144 fungi with significant variation in colonization rates.
  • The extracts from these fungi showed strong antibacterial activity, particularly against MRSA, and significant antioxidant potential, indicating their possible applications in pharmaceuticals and biotechnology.
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Pesticides have health consequences for humans, living organisms, and ecosystems. Research on biological management, with a primary focus on entomopathogens, has been accelerated by the rise in issues such as pesticide residue, soil degradation, and pest resistance. Entomopathogenic nematodes (EPNs) are among the most frequently used and commercialised biopesticides.

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Over recent years, the scientific community has acknowledged the crucial role of certain microbial strains inhabiting the intestinal ecosystem in promoting human health, and participating in various beneficial functions for the host. These microorganisms are now referred to as next-generation probiotics and are currently considered as biotherapeutic products and food or nutraceutical supplements. However, the majority of next-generation probiotic candidates pose nutritional demands and exhibit high sensitivity towards aerobic conditions, leading to numerous technological hurdles in large-scale production.

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A new area of biotechnology is nanotechnology. Nanotechnology is an emerging field that aims to develope various substances with nano-dimensions that have utilization in the various sectors of pharmaceuticals, bio prospecting, human activities and biomedical applications. An essential stage in the development of nanotechnology is the creation of nanoparticles.

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Microbes are a worthwhile organism of the earth that could be formulated as consortium which can be utilized as biofertilizers. Consortium-based bioinoculants or biofertilizers are superior to single strain-based inoculants for sustainable agricultural productivity and increased micronutrient content in yield. The aim of present study was to evaluate the effect of different combinations of beneficial bacteria that are more effective than single-based bioinoculants.

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Article Synopsis
  • Growing populations are increasing the demand for food, necessitating the need for sustainable agriculture practices.
  • Microbial consortia, which produce beneficial biostimulants, can enhance nutrient uptake and help plants cope with environmental stress, leading to improved crop productivity.
  • The review highlights the methods for assessing effective microbial combinations, as well as their formulation, application, and commercialization to support agricultural sustainability.
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Agro-environmental sustainability is based upon the adoption of efficient resources in agro-practices that have a nominal impact on the ecosystem. Insect pests are responsible for causing severe impacts on crop productivity. Wide ranges of agro-chemicals have been employed over the last 50 years to overcome crop yield losses due to insect pests.

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Lima beans () and adzuki beans () are some of the most nutritious underutilized pulses that are significant in being used as basic ingredients for the preparation of various food products. The present study aimed to determine the impact of soaking and germination on nutritional and bioactive components, in vitro protein digestibility, reducing power, metal chelating capacity, antioxidant activity, and anti-nutritional components of lima and adzuki beans. The findings showed that during the germination treatment, the in vitro protein digestibility of lima and adzuki beans increased by 14.

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Fruit crops are frequently subjected to biotic and abiotic stresses that can significantly reduce the absorption and translocation of essential elements, ultimately leading to a decrease in crop yield. It is imperative to grow fruits and vegetables in areas prone to drought, salinity, and extreme high, and low temperatures to meet the world's minimum nutrient demand. The use of integrated approaches, including supplementation of beneficial elements like silicon (Si), can enhance plant resilience under various stresses.

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In the past few decades, the pressure of higher food production to satisfy the demand of ever rising population has inevitably increased the use synthetic agrochemicals which have deterioration effects. Biostimulants containing beneficial microbes (single inoculants and microbial consortium) were found as an ideal substitute of synthetic chemical fertilizers. In recent years, microbial consortium is known as a better bioinoculant in comparison to single inoculant bioformulation because of multifarious plant growth-promoting advantages.

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The field of nanotechnology has the mysterious capacity to reform every subject it touches. Nanotechnology advancements have already altered a variety of scientific and industrial fields. Nanoparticles (NPs) with sizes ranging from 1 to 100 nm (nm) are of great scientific and commercial interest.

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Article Synopsis
  • The Bacillus genus plays a vital role in modern agriculture by promoting plant growth and sustainability through various mechanisms such as nitrogen fixation, phosphate solubilization, and growth hormone production.
  • These bacteria also serve as biocontrol agents, helping protect plants from diseases and enhancing soil fertility when used with biochar.
  • Advances in molecular biology and biotechnology have led to the development of Bacillus-based biofertilizers and biopesticides, offering sustainable alternatives to chemical inputs and supporting climate-resilient agriculture.
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Endophytic microbes are plant-associated microorganisms that reside in the interior tissue of plants without causing damage to the host plant. Endophytic microbes can boost the availability of nutrient for plant by using a variety of mechanisms such as fixing nitrogen, solubilizing phosphorus, potassium, and zinc, and producing siderophores, ammonia, hydrogen cyanide, and phytohormones that help plant for growth and protection against various abiotic and biotic stresses. The microbial endophytes have attained the mechanism of producing various hydrolytic enzymes such as cellulase, pectinase, xylanase, amylase, gelatinase, and bioactive compounds for plant growth promotion and protection.

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(1) Background: Increasing salinity, further potentiated by climate change and soil degradation, will jeopardize food security even more. Therefore, there is an urgent need for sustainable agricultural practices capable of maintaining high crop yields despite adverse conditions. Here, we tested if wheat, a salt-sensitive crop, could be a good reservoir for halotolerant bacteria with plant growth-promoting (PGP) capabilities.

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Cold stress leads to the disruption of the cellular homeostasis in plants and generation of reactive oxygen species (ROS) and productivity losses. In the present study, 94 psychrotrophic phosphorus-solubilizing bacteria with multiple plant growth-promoting (PGP) capabilities were isolated from rhizosphere of wheat. The most efficient strain EU-KL94 showing highest amount of solubilized phosphorus and maximum number of PGP attributes was identified using 16S rRNA sequencing as Ochrobactrum thiophenivorans.

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The quest for increasing agricultural yield due to increasing population pressure and demands for healthy food has inevitably led to the indiscriminate use of chemical fertilizers. On the contrary, the exposure of the crops to abiotic stress and biotic stress interferes with crop growth further hindering the productivity. Sustainable agricultural practices are of major importance to enhance production and feed the rising population.

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Globally, man-made agrochemicals plays crucial role in plant growth promotion and boost crop yield. The agrochemicals overuse leaves the detrimental damage on the environment and humans. Biostimulants developed from single or multiple microbes (archaea, bacteria, and fungi) could be the appropriate alternative of agrochemical which sustains the agriculture as well as environment.

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Abiotic stress poses a severe danger to agriculture since it negatively impacts cellular homeostasis and eventually stunts plant growth and development. Abiotic stressors like drought and excessive heat are expected to occur more frequently in the future due to climate change, which would reduce the yields of important crops like maize, wheat, and rice which may jeopardize the food security of human populations. The plant microbiomes are a varied and taxonomically organized microbial community that is connected to plants.

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Low-temperature stress can seriously impair plant physiology. Chilling injury leads to a complex array of cellular dysfunctions, and symptoms include chlorosis, sterility, loss of vigor, wilting, and even death of the plants. Furthermore, phosphorus limitations additionally halt the growth of plants.

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Microbes play crucial functions in maintaining the health and growth of the plants directly or indirectly by supplying nutrients. These microbes could be used as biofertilizers for the enhancement of soil health and growth of crops. In preset investigation, potential microbes from endophytic and rhizospheric region of growing in green slopes of Shivaliks, Himachal Pradesh were sorted out and screened for plant growth promoting attributes including phosphorus and potassium solubilization.

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