Synopsis of recent research by authors named "Aiwen Jin"
- Aiwen Jin's recent research primarily focuses on the regulation of metabolism and cellular survival mechanisms, particularly emphasizing the interactions of the tumor suppressor p53 and various metabolic pathways in response to stress conditions.
- A notable finding involves the identification of carnitine o-octanoyltransferase (CROT) as a target gene of p53 that helps promote oxidative metabolism and cell survival during nutrient starvation, highlighting p53's significant role in metabolic regulation.
- Additionally, Jin's studies on ribosomal protein RPL11 and its impact on anemia through the activation of the RP-MDM2-p53 pathway further underscore the complex connection between ribosomal function, p53 regulation, and metabolic homeostasis in a physiological context.