This study tested the hypothesis that women patients with depression should perform movements more slowly and with greater variability, and their learning rate should be lower compared with age-matched healthy adult women. Three groups of adult women subjects (aged 33-37 years, women patients with mild and major depression and healthy adult women, n = 20 in each group) performed five series (20 repetitions in each series) of a speed-accuracy hand-movement task (SAT). The mean movement speed (V) of the SAT was lower and more stable (the coefficient of variation of V was lower) in women patients with major depression compared with those with minor depression and healthy adult women during the first series of the SAT.
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