Publications by authors named "Aishwarya Korde"
Article Synopsis
- CRISPR/Cas acts like molecular scissors for precise gene editing using mechanisms like non-homologous end joining (NHEJ) or homology-directed repair (HDR), with various Cas effectors available for different applications.
- SpCas9 is the most studied version, recognized as a breakthrough for correcting genetic mutations, while newer variants like Cas12 and Cas13 are noted for their specific abilities to recognize and cleave target nucleic acids.
- The combination of CRISPR technology, diagnostics, and nanotechnology has led to the development of advanced biosensing systems capable of providing quantitative fluorescent signals for diagnostic purposes.
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