Evaluation of phytochemical constituents and sedative-hypnotic activity of the methanol leaf extract of in mice.

Background And Aim: Sedative drugs mostly cause dose-dependent depression of the central nervous system which results in hypnosis and anesthesia possibly; however, these agents are associated with some side effects ranging respiratory, digestive, immune system dysfunctions, tolerance, cognitive function deterioration, and physical dependence; hence, investigations of newer and safer agents are, therefore, imperative. The current study was aimed at investigating the sedative-hypnotic (S-H) effects of the methanol leaf extract of in mice.

Materials And Methods: Phytochemical screening of the leaf extract was conducted, and S-H activity of the plant extract was evaluated.