Publications by authors named "Aishah Snoek"

Article Synopsis
  • A study investigated whether adding group schema therapy (GST) to individual trauma-focused treatment (imagery rescripting, ImRs) improves outcomes for patients with PTSD and cluster C personality disorders (PD).* -
  • 130 adult outpatients were randomly assigned to receive either ImRs alone or ImRs plus GST, with results measured one year later to assess PTSD severity and other secondary outcomes.* -
  • Both treatment groups showed significant reductions in PTSD severity, but there was no notable difference between the two, suggesting that standard trauma-focused treatment may be the better first-line option for these patients.*
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Introduction: High dropout and low treatment attendance rates among patients with posttraumatic stress disorder (PTSD) and personality disorders (PDs) continue to pose a significant challenge. Despite numerous studies focusing on enhancing treatment attendance, the identification of consistent and reliable predictors in patients with PTSD and comorbid PDs remains limited.

Objectives: This study aims to investigate a wide range of potential predictors of treatment attendance, encompassing demographic, patient-severity, treatment, and therapist-related variables in patients with PTSD and comorbid borderline and/or cluster C PDs.

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Comorbidity between posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD) is surrounded by diagnostic controversy and although various effective treatments exist, dropout and nonresponse are high. By estimating the network structure of comorbid PTSD and BPD symptoms, the current study illustrates how the network perspective offers tools to tackle these challenges. The sample comprised of 154 patients with a PTSD diagnosis and BPD symptoms, assessed by clinician-administered interviews.

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: Although personality disorders are common in PTSD patients, it remains unclear to what extent this comorbidity affects PTSD treatment outcome. : This constitutes the first meta-analysis investigating whether patients with and without comorbid personality disorders can equally benefit from psychotherapy for PTSD. : A systematic literature search was conducted in PubMed, EMBASE, PsychINFO and Cochrane databases from inception through 31 January 2020, to identify clinical trials examining psychotherapies for PTSD in PTSD patients with and without comorbid personality disorders (PROSPERO reference CRD42020156472).

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Background: Neural alterations related to treatment outcome in patients with both post-traumatic stress disorder (PTSD) and comorbid personality disorder are unknown. Here we describe the protocol for a neuroimaging study of treatment of patients with PTSD and comorbid borderline (BPD) or cluster C (CPD) personality disorder traits. Our specific aims are to 1) investigate treatment-induced neural alterations, 2) predict treatment outcome using structural and functional magnetic resonance imaging (MRI) and 3) study neural alterations associated with BPD and CPD in PTSD patients.

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Posttraumatic stress disorder (PTSD) is a serious and relatively common mental disorder causing a high burden of suffering. Whereas evidence-based treatments are available, dropout and non-response rates remain high. PTSD and Cluster C personality disorders (avoidant, dependent or obsessive-compulsive personality disorder; CPD) are highly comorbid and there is evidence for suboptimal treatment effects in this subgroup of patients.

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Article Synopsis
  • This study focuses on the effectiveness and cost-efficiency of combining Eye Movement Desensitization and Reprocessing (EMDR) with Dialectical Behavior Therapy (DBT) for treating patients with both PTSD and Borderline Personality Disorder (BPD), compared to EMDR alone.
  • It will be conducted as a randomized controlled trial with 126 adult participants, measuring various neurobiological factors (like cortisol and protein levels) to understand how they influence an individual's response to treatment.
  • This research aims to identify which therapy is more effective for specific patients and establish better treatment protocols for those with the complex comorbidity of PTSD and BPD.
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