Investigating the impact of perceived social stigmatization and social appearance anxiety on quality of life among patients with facial skin diseases.

Background: This study investigates the interplay between perceived social stigmatization, social appearance anxiety, and quality of life in individuals with facial skin diseases. Furthermore, it undertakes the psychological and social impact of visible skin diseases, such as acne, atopic dermatitis, rosacea, enlarged pores, and vitiligo, on individuals' quality of life. These conditions not only cause physical discomfort but also lead to feelings of sadness, anxiety, and low self-esteem.

Urdu translation and validation of clinically useful anxiety outcome scale in Pakistan: 'An observational study'.

Objective: To translate and evaluate the psychometric properties of the Clinically Useful Anxiety Outcome Scale on Urdu-speaking population.

Methods: The observational validation study was conducted in Rawalpindi and Islamabad, Pakistan, from January 2018 to December 2019 in two phases. In the first phase, the Clinically Useful Anxiety Outcome Scale was forward and backward translated, while in the second phase, the translated scale was validated on a sample comprising subjects in clinical and nonclinical settings.

Meckel Gruber Syndrome: Second trimester diagnosis of a case in a non-consanguineous marriage.

Meckel-Gruber Syndrome (MKS) is a rare, autosomal recessive genetic disorder, incompatible with life. It is characterized by enlarged polycystic kidneys and post axial polydactyly. Foetal or neonatal death is caused by pulmonary hypoplasia.