Short and long term prediction of seizure freedom in drug-resistant focal epilepsy surgery.

Background: The selection of candidates for drug-resistant focal epilepsy surgery is essential to achieve the best post-surgical outcomes.

Objective: To develop two prediction models for seizure freedom in the short and long-term follow-up and from them to create a risk calculator in order to individualize the selection of candidates for surgery and future therapies in each patients.

Methods: A sample of 64 consecutive patients who underwent epilepsy surgery at two Cuban tertiary health institutions between 2012 and 2020 constituted the basis for the prediction models.

Surgical Outcome in Extratemporal Epilepsies Based on Multimodal Pre-Surgical Evaluation and Sequential Intraoperative Electrocorticography.

Objective: to present the postsurgical outcome of extratemporal epilepsy (ExTLE) patients submitted to preoperative multimodal evaluation and intraoperative sequential electrocorticography (ECoG).

Subjects And Methods: thirty-four pharmaco-resistant patients with lesional and non-lesional ExTLE underwent comprehensive pre-surgical evaluation including multimodal neuroimaging such as ictal and interictal perfusion single photon emission computed tomography (SPECT) scans, subtraction of ictal and interictal SPECT co-registered with magnetic resonance imaging (SISCOM) and electroencephalography (EEG) source imaging (ESI) of ictal epileptic activity. Surgical procedures were tailored by sequential intraoperative ECoG, and absolute spike frequency (ASF) was calculated in the pre- and post-resection ECoG.

Mortality in patients with refractory temporal lobe epilepsy at a tertiary center in Cuba.

Objectives: We aimed to investigate the prevalence and risk of mortality in patients with refractory temporal lobe epilepsy.

Methods: Eligible patients included all adults referred to the National Institute of Neurology (NIN) in Havana, Cuba. All patients were followed up for 9 years.

Lateralizing value of ictal dorsiflexion of the great toe in refractory partial epilepsy.

Introduction: A case of ictal dorsiflexion of the great toe was reported two years ago in a patient with insular cortex seizures. Since that publication, series of patients with the sign have not been reported.

Objectives: The aims of the present study were to describe the frequency of the ictal sign and to evaluate positive predictive value (PPV) to lateralize the epileptogenic zone.