Publications by authors named "Airu Chang"
Article Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a serious lung condition linked to damage in alveolar epithelial cells, potentially caused by mitochondrial imbalance.
- The study found that the absence of the protein PTPN21 worsens lung fibrosis by promoting increases in cell count and extracellular matrix proteins.
- PTPN21 loss leads to impaired mitochondrial function and autophagy in lung cells, while its overexpression shows some protective effects, indicating its importance in regulating lung fibrosis.
