Publications by authors named "Airi Hitsuji"
Effective induction of death in mesothelioma cells with magnetite nanoparticles under an alternating magnetic field.
Mater Sci Eng C Mater Biol Appl
December 2017
Article Synopsis
- This study explores the use of magnetite nanoparticles (MNPs) for inducing cell death in different types of human mesothelioma cells when exposed to an AC magnetic field.
- All three types of mesothelioma cells incorporated MNPs, but MSTO-211H cells showed lower MNP uptake compared to NCI-H28 and NCI-H2052.
- The results indicated that MSTO-211H cells exhibited significant cell death even at lower temperatures, while NCI-H28 and NCI-H2052 cells experienced higher mortality due to a greater heat increase from more MNPs, suggesting that MNP cellular uptake is crucial for effective mesothelioma treatment.
Induction of Cell Death in Mesothelioma Cells by Magnetite Nanoparticles.
ACS Biomater Sci Eng
August 2015
Nanoparticle uptake and cell death following addition of magnetite nanoparticles (MNPs) with a diameter of ∼10 nm were evaluated in three histological types of human mesothelioma cells, NCI-H28 (epithelioid), NCI-H2052 (sarcomatoid), and MSTO-211H (biphasic) cells, and human breast cancer MCF-7 cells. Dose-dependent cell death was observed in MSTO-211H cells but not in MCF-7 cells, although cellular uptake of MNPs was observed in both cell types. Mesothelioma NCI-H28 and NCI-H2052 cells showed behavior more similar to that of breast cancer MCF-7 cells than that of mesothelioma MSTO-211H cells.
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