Publications by authors named "Aiqin Sheng"
The transient receptor potential canonical 6 (TRPC6) channel, a nonselective cation channel that allows the passage of Ca, plays an important role in renal diseases. TRPC6 is activated by Ca influx, oxidative stress, and mechanical stress. Studies have shown that in addition to glomerular diseases, TRPC6 can contribute to renal tubular disorders, such as acute kidney injury, renal interstitial fibrosis, and renal cell carcinoma (RCC).
View Article and Find Full Text PDFPurpose: To assess the consistencies of anti-Toxocara IgG (T-IgG) and Goldmann-Witmer coefficient (GWC) between paired aqueous humor (AH) and vitreous samples from patients with clinically suspected ocular toxocariasis (OT).
Design: Inter-test reliability assessment.
Methods: A total of 47 patients with clinically suspected OT who underwent vitrectomy were included.
Introduction: The tamponade of silicone oil (SO) can affect both the structure and blood flow of the retina. However, there are few studies on the effect of SO tamponade on choroidal blood flow. Our study aimed to compare the effects of SO tamponade on the choroidal vascular index (CVI) and choroidal thickness (CT) in patients with unilateral rhegmatogenous retinal detachment (RRD) with operated eyes and fellow healthy eyes.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates a new surgical method using an inverted pedicled internal limiting membrane (ILM) flap connected to the optic disc to treat large macular holes (MHs) in patients.
- Twelve patients with substantial MHs (>600 µm) underwent this procedure, where the ILM was carefully manipulated and repositioned, resulting in full closure of all holes with no complications.
- Post-surgery, there was a significant improvement in best-corrected visual acuity (BCVA), highlighting the technique's effectiveness and safety for addressing large MHs.
Transcription initiation factor IIB (TFIIB) is an ideal factor to localize core promoters and plays a central role in the assembly of the pre-initiation complex. Previous studies showed that the assembly of TFIIB played an important role in rat ischemic brain injury. To elucidate the expression and possible functions of TFIIB in retina lesion and repair, we performed an optic nerve crush (ONC) model in adult rats.
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