Urine Output as a Novel Predictor for In-Hospital Mortality in Acute Pulmonary Embolism Patients: Training With the MIMIC Database and Validation With Independent Cohort.

Identifying high-risk patients with acute pulmonary embolism is vital for improving disease prognosis. However, current guidelines and research on risk factors are insufficient to meet clinical needs. This study was aimed at exploring novel risk factors to predict in-hospital mortality.

NK cell-based immunotherapy for hepatocellular carcinoma: Challenges and opportunities.

Hepatocellular carcinoma (HCC) remains one of the most challenging malignancies globally, characterized by significant heterogeneity, late-stage diagnosis, and resistance to treatment. In recent years, the advent of immune-checkpoint blockades (ICBs) and targeted immune cell therapies has marked a substantial advancement in HCC treatment. However, the clinical efficacy of these existing therapies is still limited, highlighting the urgent need for new breakthroughs.