Biomechanical analysis of scoliosis correction under the influence of muscular and external forces.

(1) Background: External force orthopedics and the strengthening of paraspinal muscles through exercise are common orthopedic methods for adolescent scoliosis, yet the synergetic mechanism of the two in orthopedic correction remains unclear. (2) Methods: A three-dimensional finite element model of the scoliotic spine was established to accurately simulate the mechanical properties of tissues such as the spine, intervertebral discs, and ribs. By applying external forces in different directions to the scoliosis model, the orthopedic effects of these forces on scoliosis were analyzed.

Prosthesis optimization and mechanical analysis of artificial lumbar disc replacement.

Background: Artificial lumbar disc replacement is an effective method for the treatment of lumbosacral degenerative diseases. An appropriate artificial intervertebral disc device is of great significance for the maintenance of spinal stability and activity.

Methods: Two finite element models of ProDisc-L prosthesis replacement and improved prosthesis replacement were constructed by using the finite element model of complete lumbar L1-L5 segment established by CT image data.

Prenatal nicotine exposure results in the myocardial fibrosis in the adult male offspring rats.

Our previous study showed that prenatal nicotine exposure could increase the heart rate of adult male offspring rats, but little is known about the mechanism. The aim of this study was to investigate the mechanism. Nicotine was subcutaneously administered to pregnant rats at a dose of 1.