Fungal Allergen and Mold Allergy Diagnosis: Role and Relevance of Alt a 1 Protein Family.

is a genus of worldwide fungi found in different habitats such as soil, the atmosphere, plants or indoor environments. species are saprobic-largely involved in the decomposition of organic material-but they can also act as animal pathogens, causing disease in humans and animals, developing infections, toxicosis and allergic diseases. is considered one of the most important sources of fungal allergens worldwide and it is associated with severe asthma and respiratory status.

The Quantification of IgG Specific to α-Gal Could Be Used as a Risk Marker for Suffering Mammalian Meat Allergy.

The alpha-Gal Syndrome is a delayed meat allergy characterized by the presence of sIgE against α-Gal epitope. It is known that the α-Gal present in tick saliva induces the sensitization to this epitope ending in the production of sIgG and sIgE to α-Gal. It could be considered that the more times a person is bitten by tick species, the higher the probability of making the switch from sIgG to sIgE to α-Gal and developing allergy, but it is no clear when the switch occurs.

Purified Native and Recombinant Major Allergen (Alt a 1) Induces Allergic Asthma in the Murine Model.

Aeroallergens such us the spores of are described as the most important agents associated with respiratory allergies and severe asthma. Various experimental models of asthma have been developed using extracts to study the pathogenesis of asthma, establishing the main parameters that trigger the asthmatic response. In this study, we describe a mouse model of asthma induced only by Alt a 1.

The Major Allergen (Asp n 3) DNA-Specific Sequence Is a Reliable Marker to Identify Early Fungal Contamination and Postharvest Damage in Fruit.

The aim of this work was to study the value of the main allergen Asp n 3 of as a molecular marker of allergenicity and pathogenicity with the potential to be used in the identification of as a contaminant and cause of spoilage of Real-time polymerase chain reaction (RT-PCR) was used for the amplification of Asp n 3 gene. Two pairs of primers were designed: one for the amplification of the entire sequence and another one for the amplification of the most conserved region of this peroxisomal protein. The presence of was demonstrated by the early detection of the allergenic protein Asp n 3 coding gene, which could be considered a species-specific marker.