Publications by authors named "Aina Rill-Hinarejos"
Cell Rep Med
November 2024
Article Synopsis
- The study investigates how the diversity of chimeric antigen receptor (CAR)-T cells affects clinical outcomes in treating B cell acute lymphoblastic leukemia (B-ALL).
- Researchers analyzed clonal dynamics and gene expression using single-cell techniques in patients receiving CD19CAR-T cells, revealing notable differences in how these T cells behave during treatment.
- Key findings include a higher CD4:CD8 ratio in successful patients' T cells at infusion and an expansion of cytotoxic T cells linked to better treatment responses across different patient cohorts.
