Publications by authors named "Aimie Peek"

The aim of this study was to systematically review prior research investigating the effects of contact/collision sport participation on neurometabolite levels in the absence of concussion. Four online databases were searched to identify studies that measured neurometabolite levels in contact/collision sport athletes (without concussion) using proton ( H) or phosphorus ( P) magnetic resonance spectroscopy (MRS). All study designs were acceptable for inclusion.

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Article Synopsis
  • - This study investigates the relationship between elevated levels of Gamma-aminobutyric acid (GABA+) and chronic migraines to determine whether the increase in GABA+ contributes to or results from chronic migraine symptoms.
  • - Over a 3-month period, researchers monitored 18 chronic migraine patients as their treatment was adjusted, assessing changes in migraine frequency, intensity, and disability alongside GABA+ levels using magnetic resonance spectroscopy (MRS).
  • - Findings indicated that improvements in migraine symptoms were linked to increased GABA+ levels in the anterior cingulate cortex, while no changes were noted in the posterior cingulate gyrus; those treated with CGRP-monoclonal antibodies experienced greater increases in GABA+ levels and reductions
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Objectives: A core outcomes set (COS) for whiplash-associated disorders (WADs) has been proposed to improve consistency of outcome reporting in clinical trials. Patient-reported disability was one outcome of interest within this COS. The aim of this review was to identify the most suitable tools for measuring self-reported disability in WAD based on clinimetric performance.

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Background: Imaging for low back pain is widely regarded as a target for efforts to reduce low-value care.

Objective: We aimed to estimate the prevalence of the overuse and underuse of lumbar imaging in patients presenting with low back pain to the emergency department (ED).

Methods: This was a retrospective chart review study of five public hospital EDs in Sydney, Australia, in 2019-20.

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Treatment outcomes for migraine and other chronic headache and pain conditions typically demonstrate modest results. A greater understanding of underlying pain mechanisms may better inform treatments and improve outcomes. Increased GABA+ has been identified in recent studies of migraine, however, it is unclear if this is present in other headache, and pain conditions.

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The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details are often not fully reported, making it difficult to assess MRS studies on a standardized basis.

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Objective: To determine the effectiveness of hip arthroscopic surgery for the treatment of femoroacetabular impingement syndrome (FAI).

Design: Systematic review with meta-analysis.

Data Sources: We performed electronic database searches in MEDLINE, Embase, SPORTDiscus, CINAHL, Cochrane Central Register for Controlled Trials (CENTRAL), Web of Science, Scopus, the WHO International Clinical Trials Registry Platform and ClinicalTrials.

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Background: A proposed mechanism of chronic pain is dysregulation between the main inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system. The level of these neurometabolites appears to differ in individual studies of people with pain compared to pain-free controls across different pain conditions. However, this has yet to be systematically investigated.

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Objectives: Choosing Wisely holds promise for increasing awareness of low-value care in physiotherapy. However, it is unclear how physiotherapists' view Choosing Wisely recommendations. The aim of this study was to evaluate physiotherapists' feedback on Choosing Wisely recommendations and investigate agreement with each recommendation.

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Objectives: Non-specific shoulder pain (NSSP) is often persistent and disabling leading to high socioeconomic costs. Cervical manipulation has demonstrated improvements in patients with NSSP, although risks associated with thrust techniques are documented. Thoracic manual therapy (TMT) may utilise similar neurophysiological effects with less risk.

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