Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis.

Objective: To evaluate neurotrophin (NT) expression in the endometrium of women with and without endometriosis.

Design: Prospective, cross-sectional, translational study.

Setting: Academic hospital.

Discontinuation of rLH two days before hCG may increase the number of oocytes retrieved in IVF.

Background: Administration of recombinant luteinizing hormone (rLH) in controlled ovarian hyperstimulation may benefit a subpopulation of patients. However, late follicular phase administration of high doses of rLH may also reduce the size of the follicular cohort and promote monofollicular development.

Methods: To determine if rLH in late follicular development had a negative impact on follicular growth and oocyte yield, IVF patients in our practice who received rFSH and rLH for the entire stimulation were retrospectively compared with those that had the rLH discontinued at least two days prior to hCG trigger.