The use of collagen cross-linking agents to enhance dentin bond strength.

Unlabelled: Type I collagen is a major component of the hybrid layer, and improvement of its mechanical properties may be advantageous during bonding procedures.

Objective: To investigate the effect of three different cross-linking agents (Glutaraldehyde [GD], Grape seed extract [GSE], and Genipin [GE]) on the tensile bond strength (TBS) of resin-dentin bonds.

Materials And Methods: Sixty-four sound human molars were collected and their occlusal surfaces were ground flat to expose dentin.