Spondylectomy for Giant Cell Tumor After Denosumab Therapy.

Study Design: A case report.

Objective: To report a case of the lumbar giant cell tumor (GCT) utilizing a new clinical treatment modality (denosumab therapy), which showed a massive tumor reduction combined with the L4 spondylectomy.

Summary Of Background Data: There are some controversies about spinal GCT treatments.

Prognostic role of positive peritoneal cytology in patients with resectable gastric cancer.

Objective: To evaluate the prognostic value of positive peritoneal lavage in patients with gastric cancer without signs of peritoneal or hematogenous spread.

Methods: We evaluated patients with gastric adenocarcinoma treated with curative intent operation. The peritoneal lavage was classified as positive or negative for neoplastic cells.

Endoscopic mucosal resection of early gastric cancer: initial experience with two technical variants.

Background: When performed in carefully selected cases, the endoscopic treatment of early gastric cancer yields results which are comparable to the conventional surgical treatment, but with lower morbidity and mortality and better quality of life. Several technical options to perform endoscopic mucosal resection have been described and there is a large amount of accumulated experience with this procedure in eastern countries. In western countries, particularly in Brazil, technical limitations associated with the small number of cases of early gastric cancer reflect the little experience with this therapeutic mode.