Publications by authors named "Ailsa Pickering"
Article Synopsis
- In response to a national mpox outbreak in England, children exposed to the virus were vaccinated with the MVA-BN smallpox vaccine to evaluate its safety and immune response.
- A study assessed 87 children who received the vaccine, finding no serious adverse events or mpox infections post-vaccination; reactogenicity data showed varying symptoms, with many reporting local reactions.
- Blood tests confirmed the presence of poxvirus IgG antibodies in all participants, indicating a robust immune response, with measures suggesting strong humoral responses to virus proteins at both one and three months after vaccination.
Background: Appropriate medication use is essential in ensuring optimal pharmacotherapeutic outcomes. It is mistakenly assumed that adults can swallow solid oral dosage forms (SODFs, e.g.
View Article and Find Full Text PDFTablets are safer, more convenient and cheaper than liquid medications. Children and young people (CYP) often remain on liquids due to habit, reluctance to change or staff and parents' lack of knowledge about switching to tablets. We describe a quality improvement project to train staff and embed a system of converting eligible children to tablet medication.
View Article and Find Full Text PDFBackground: Congenital cytomegalovirus (cCMV) infection is an important illness that is a common cause of hearing loss in newborn infants and a major cause of disability in children. For that reason, treatment of symptomatic patients with either ganciclovir or its pro-drug valganciclovir is recommended. Treatment duration of 6 months has been shown to be more beneficial than shorter courses; however, there is uncertainty regarding emergence of resistance strains, secondary effects and long term sequelae.
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