Genetic diversity analysis of benzimidazole resistance-associated genes in Haemonchus contortus from four regions in southern Xinjiang.

To assess the genetic diversity of the I β-tubulin haplotype gene associated with benzimidazoles (BZs) resistance in Haemonchus contortus populations across southern Xinjiang, the sampled populations from four distinct areas to detect the BZs resistance-related I-β tubulin gene and analyse its genetic sequences and structure. The results revealed substantial haplotype diversity and nucleotide polymorphisms across the four populations, with nucleotide diversity (Pi) ranging from 0.03471 to 0.

The first molecular detection of benzimidazole resistance in Haemonchus contortus from sheep in Hejing and Minfeng counties of Southern Xinjiang.

To understand the benzimidazole (BZ) resistance of Haemonchus contortus in Southern Xinjiang, three single nucleotide polymorphisms (SNPs) designated as F167Y, E198A, and F200Y, in the isotype-1 β-tubulin gene which are associated with BZ resistance, were investigated for H. contortus populations from sheep in Hejing and Minfeng counties of Southern Xinjiang. In brief, a total of 190 H.