Publications by authors named "Ailish Garrett"
Background: Prior research demonstrates Crohn's disease patients often do well in pregnancy; however, less is known about the risk of flare in the postpartum period.
Methods: A retrospective chart review was conducted at a tertiary care inflammatory bowel disease center. All pregnant women with Crohn's disease who were followed in the postpartum period, defined as 6 months after delivery, were included.
Background: Ustekinumab was approved for moderate and severe Crohn's disease (CD) in 2016, but little is known about long-term outcomes.
Methods: A retrospective study evaluated all patients with CD treated with ustekinumab, including patients with reinduction. C-reactive protein (CRP), Harvey-Bradshaw Index (HBI), Short Inflammatory Bowel Disease (SIBDQ), and endoscopy outcomes were collected prospectively.
Article Synopsis
- The study focused on identifying factors that lead to nonadherence to biologic therapy in patients with inflammatory bowel disease (IBD), specifically Crohn's disease (CD) and ulcerative colitis (UC).
- About 460 patients were evaluated, revealing that 69% adhered to their treatment, with lower adherence rates in those with CD compared to UC.
- Key risk factors for nonadherence included having CD, being on Medicaid insurance, and having a history of psychiatric issues, smoking, or prior biologic therapy; the likelihood of nonadherence increased with the number of risk factors present.