Publications by authors named "Ailin Xiong"
The microbiome is a collection of genomes from microbiota, including all microorganisms in a niche, through direct and indirect interactions with the host. Certain microorganisms can exist in areas conventionally considered to be sterile, such as the bone matrix. Osseous microbiota dysbiosis caused by host-microbiome perturbation or external infections may ultimately lead to osteomyelitis, a bone inflammatory disorder.
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- Recent studies identify specific peripheral neurons for itch transmission, but spinal interneuron roles remain debated.
- Research shows that spinal somatostatin-positive (SOM) excitatory interneurons are crucial for transmitting itch sensations, as their ablation significantly reduces scratching responses to pruritogens.
- Findings suggest parallel pathways in spinal itch processing, highlighting a novel mechanism where SOM neurons influence itch perception through interactions with inhibitory interneurons.