LncRNA HOTAIR enhances RCC2 to accelerate cervical cancer progression by sponging miR-331-3p.

Purpose: Long noncoding RNAs (lncRNAs) have been gradually regarded as influential indicators of various cancers. The present study aimed to identify the effects of lncRNA HOTAIR on cervical cancer progression.

Methods: RNA and protein expressions were quantified by RT-qPCR and western blot assays.

MicroRNA-331-3p inhibits proliferation and metastasis of ovarian cancer by targeting RCC2.

Introduction: Epithelial ovarian carcinoma (EOC) is one of the most lethal gynecologic malignancies, with a poor 5-year survival rate. Numerous studies have shown that microRNAs participate in the malignant behavior of ovarian cancer cells by directly targeting multiple oncogenes or tumor suppressor genes.

Material And Methods: Reverse transcription-PCR was used to determine the level of miR-331-3p in EOC.