Infant Maltreatment Induces Early Alterations in Adrenal Glands and Stress Response in Juvenile Rat Offspring.

Chronic stressors, such as infant maltreatment during early development, can have long-lasting effects on an individual's health and stress-coping abilities across the lifespan. In this study, we applied the scarcity-adversity model (SAM) to Wistar rats from postnatal days (PND) 8 to 12 to evaluate the impact of scarcity condition on adrenal glands morphology and stress response in juvenile offspring (PND 21-35) of both sexes. Our results demonstrate that SAM exposure leads to significant alterations in the adrenal glands of offspring.