Publications by authors named "Aileen Lim"

Article Synopsis
  • The study investigates the effectiveness of the modified Hospital Frailty Risk Score (mHFRS) in identifying frail hospitalized older adults, comparing it with the original Hospital Frailty Risk Score (HFRS) and the Clinical Frailty Scale (CFS).
  • A review of 3,042 patients over 65 years old was conducted, revealing that the CFS identified 46.3% as frail, with frail patients generally being older, more likely female, and having longer hospital stays and higher mortality rates.
  • The mHFRS showed a significant correlation with both CFS and HFRS, proving to be effective in classifying patients, especially identifying non-frail individuals, and suggesting it as a
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Introduction: Frailty has an important impact on the health outcomes of older patients, and frailty screening is recommended as part of perioperative evaluation. The Hospital Frailty Risk Score (HFRS) is a validated tool that highlights frailty risk using 109 International Classification of Diseases, 10th revision (ICD-10) codes. In this study, we aim to compare HFRS to the Charlson Comorbidity Index (CCI) and validate HFRS as a predictor of adverse outcomes in Asian patients admitted to surgical services.

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Aim: Frailty results from age-associated declines in physiological reserve and function and is prevalent in older people. Our aim is to examine the association of the Hospital Frailty Risk Score (HFRS) with adverse events in older patients hospitalized with community-acquired pneumonia (CAP) and hypothesise that frailty is a comparable predictor of outcomes in CAP versus traditional severity indices such as CURB-65.

Methods: Retrospective review of electronic medical records in patients ≥65 years with CAP admitted to a tertiary hospital from 1 January to 30 April 2021.

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Objective: To determine how HIV+ individuals access safety and knowledge of drug interactions related to complementary and alternative medicine (CAM).

Methods: We conducted two separate focus group sessions with HIV+ users of complementary therapies. A total of 8 men participated at an urban health centre.

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Both odontoglossum ringspot virus (ORSV) and tobacco mosaic virus (TMV) were investigated as expression viral vectors for the expression of a neuropeptide nocistatin. Chimeras of ORSV and TMV were constructed by fusion of 17 amino acids of mouse nocistatin (mNST) to the C-terminal of the coat protein (CP) gene via a Factor Xa cleavage linker to yield ORSV-mNST and TMV-mNST. Expression of the mNST peptide was demonstrated by immuno-transmission electron microscopy, western blot, mass spectrometry and radioimmunoassay.

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