Publications by authors named "Aike Xu"
Article Synopsis
- The study analyzed 2042 twin pregnancies from IVF and ICSI to understand risk factors for very early preterm (before 28 weeks) and early preterm births (between 28-34 weeks).
- It categorized births based on gestational age, finding that 4.36% were very early preterm, 12.14% early preterm, and the vast majority (83.50%) were ongoing pregnancies at 34 weeks or more.
- Key risk factors identified for very early preterm births included cervical cerclage, history of miscarriage or premature birth, certain uterine conditions, and a higher body mass index, while factors like polycystic ovary syndrome (PCOS) and specific uterine
Objective: To investigate the chromosome abnormality rates and clinical pregnancy outcomes after preimplantation genetic testing for aneuploidy (PGT-A) using either the progestin-primed ovarian stimulation (PPOS) protocol or the gonadotropin-releasing hormone (GnRH) antagonist protocol.
Methods: The study included 431 PGT-A cycles in which controlled ovarian stimulation was performed using the PPOS protocol (n = 320 cycles) or GnRH antagonist protocol (n = 111 cycles) between January 2018 and December 2021. Frozen embryo transfer was subsequently performed in 307 cycles with transferable blastocysts.
Article Synopsis
- This study assessed the impact of different durations of growth hormone pretreatment on assisted reproductive therapy outcomes in patients with diminished ovarian reserve (DOR), involving a total of 1459 participants.
- Results indicated that patients receiving GH pretreatment (especially those in the 1-month and 2-month groups) had a significantly higher number of oocytes retrieved compared to a control group without GH treatment.
- However, extending GH pretreatment beyond 1 month did not yield additional benefits in terms of oocyte retrieval, suggesting that while GH pretreatment is beneficial, longer durations may not be necessary for improved outcomes.
Article Synopsis
- The study investigates whether injecting women's own platelet-rich plasma (PRP) gel into the uterus can enhance endometrial thickness (EMT) and improve success rates for frozen-thawed embryo transfers (FET) in women with thin endometrium.
- A total of 111 women aged 25-44, who previously experienced canceled cycles or low EMT (<7 mm), participated, with 47 receiving PRP gel and the rest acting as controls.
- Results showed that the PRP group had a significantly thicker endometrium (6.7 mm vs. 6.3 mm) and higher pregnancy rates (38.3% vs. 18.5%), though the miscarriage rate did not significantly change.
To investigate the effects of pretreatment with long-acting gonadotropin-releasing hormone agonist (GnRH-a) before frozen-thawed embryo transfer (FET) on pregnancy outcomes in patients after minimal-mild (stages I-II) peritoneal endometriosis surgery. A retrospective cohort study was performed from March 2018 to May 2019. Overall, 274 patients met inclusion criteria of undergoing FET after minimal/mild peritoneal endometriosis surgery.
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