Publications by authors named "Aikaterini Gianneli"
Infect Genet Evol
October 2017
Article Synopsis
- Hepatitis C virus (HCV) is a member of the Flaviviridae family and features a complex structure with a capsid and lipid bilayer, including various viral particle forms in infected patients.
- HCV non-enveloped capsid-like particles (HCVne) are generated from the viral core protein, which contains specific motifs that facilitate their entry into liver cells through clathrin-mediated endocytosis.
- The YXXΦ motif in the HCV core is essential for maintaining the structure of HCVne and plays a critical role in cellular signaling and enhancing viral replication by enabling proper trafficking of HCVne to lipid droplets.
