Publications by authors named "Aijun Kong"
Article Synopsis
- Aristolochic acids (AA), compounds from the Aristolochiaceae plant family, are known for causing kidney damage, yet this study focuses on their potential neurotoxicity during development.
- Continuous exposure to non-harmful concentrations of AA in embryonic zebrafish led to increased larval hyperactivity and changes in motor neuron behavior, particularly within the critical 8-24 hour post-fertilization window.
- AA exposure resulted in eye size changes and affected the expression of vision-related genes, indicating a distinct neurotoxic impact separate from its kidney-related effects.
Tissue distribution of tetrabromobisphenol A and cadmium in mixture inhalation exposure.
Toxicol Ind Health
February 2019
Article Synopsis
- The study investigates how inhaling a mixture of Tetrabromobisphenol A (TBBPA) and cadmium chloride (CdCl) affects metabolic kinetics in male mice.
- TBBPA accumulates significantly in the brain, liver, and spleen, while cadmium primarily concentrates in the liver, kidney, and testis, with both showing increased levels over time during exposure.
- Four weeks after exposure ended, the concentrations of TBBPA and cadmium in various organs were found to be higher than during the exposure, raising concerns about long-term health risks, especially respiratory diseases, for workers in e-waste recycling.
Brominated flame retardants (BFRs) and heavy metals (HMs) are two main types of pollutants in electronic waste recycling sites, which are also ubiquitously detectable in environmental media and human tissues. However, the adverse health effects of exposure to the mixture of these types of pollutants are unknown. In this study, we investigated the reproductive toxicity of a mixture of decabromodiphenyl ether (BDE-209), tetrabromobisphenol A, cadmium chloride, and lead acetate (PbAc) at the environmental relevant levels.
View Article and Find Full Text PDF