Co-creation with AI: A painting therapy program aimed at ameliorating attention deficits in children with ADHD.

Art therapy has been proven to be efficacious in alleviating symptoms of children diagnosed with Attention Deficit Hyperactivity Disorder (ADHD), with the advent of artificial intelligence providing new technological means to engage and increase the participation levels of ADHD children. Nonetheless, research on the application of AI in art therapy remains scant. This study, predicated on a method involving ADHD children co-creating art with AI, has devised a therapeutic activity aimed at ameliorating their attention deficits.

The application and impact of artificial intelligence technology in graphic design: A critical interpretive synthesis.

In the field of graphic design, the application of Artificial Intelligence (AI) is reshaping the design process. This study employs the Critical Interpretive Synthesis (CIS) approach to explore the impacts and challenges of AI on graphic design. Through a comprehensive review of 33 papers, this research reveals four research paradigms of AI in graphic design: Artificial Intelligence Driven Design Automation and Generation (AIDAG), Artificial Intelligence Assisted Graphic Design and Image Processing (AGDIP), Artificial Intelligence in Art and Creative Design Processes (AACDP), and Artificial Intelligence Enhanced Visual Attention and Emotional Response Modeling (AVERM).

Epigenetic changes driven by environmental pollutants in lung carcinogenesis: a comprehensive review.

Lung cancer remains the leading cause of cancer-related mortality globally, with environmental pollutants identified as significant risk factors, especially for nonsmokers. The intersection of these pollutants with epigenetic mechanisms has emerged as a critical area of interest for understanding the etiology and progression of lung cancer. Epigenetic changes, including DNA methylation, histone modifications, and non-coding RNAs, can induce alterations in gene expression without affecting the DNA sequence and are influenced by environmental factors, contributing to the transformation of normal cells into malignant cells.

Deciphering the role of miRNA-134 in the pathophysiology of depression: A comprehensive review.

This study summarizes the significance of microRNA-134 (miRNA-134) in the pathophysiology, diagnosis, and treatment of depression, a disease still under investigation due to its complexity. miRNA-134 is an endogenous short non-coding RNA that can bind to the 3' untranslated region (3'UTR) of miRNA-134, inhibiting gene translation and showing great potential in the regulation of mood, synaptic plasticity, and neuronal function. This study included 15 articles retrieved from four English-language databases: PubMed, Embase, The Cochrane Library, and Web of Science, and three Chinese literature databases: CNKI, Wanfang, and Chinese Science and Technology Periodical Database (VIP).

Xanthine negatively regulates c-MYC through the PI3K/AKT signaling pathway and inhibits the proliferation, invasion, and migration of breast cancer cells.

Background Aim: Breast cancer is a prevalent and aggressive malignancy associated with elevated mortality rates worldwide. Dysregulation of the c-MYC oncogene and aberrant activation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway are common features in breast cancer progression, rendering them attractive therapeutic targets. Here, we assessed the effects of the plant derivative, xanthine, on breast cancer cells and explored the molecular mechanisms underlying its activity.

Partitioned Microneedle Patch Based on NO Release and HSP Inhibition for mPTT/GT Combination Treatment of Melanoma.

Photothermal therapy (PTT) shows promise in cancer treatments due to its good spatiotemporal selectivity and minimal invasiveness. However, PTT has some problems such as excessive heat damage to normal tissues, tumor thermo-resistance caused by heat shock proteins (HSPs), and limited efficacy of monotherapy. Here, we construct a patch named "partitioned microneedles" (PMN-SNAP/CuS), which separates the "catalyst" bovine serum albumin-based copper sulfide nanoparticles (CuS@BSA NPs) and the "reactant" -nitroso--acetylpenicillamine (SNAP) into different regions of microneedles, for enhancing mild PTT (mPTT) of melanoma.

The potential of arts therapies in Parkinson's disease rehabilitation: A comprehensive review.

Background And Purpose: Parkinson's disease (PD) causes a decline in motor function, cognitive decline, and impacts the mental health of patients. Due to the high cost and side effects of conventional treatments, the medical community has begun to explore safer and more cost-effective alternative therapies. In this context, arts therapies have gained increasing attention as innovative treatments.

Impact of geochemistry and microbes on the methylmercury production in mangrove sediments.

Unraveling the geochemical and microbial controls on methylmercury (MeHg) dynamics in mangrove sediments is important, as MeHg can potentially pose risks to marine biota and people that rely on these ecosystems. While the important role of sulfate-reducing bacteria in MeHg formation has been examined in this ecologically important habitat, the contribution of non-Hg methylating communities on MeHg production remains particularly unclear. Here, we collected sediment samples from 13 mangrove forests in south China and examined the geochemical parameters and microbial communities related to the Hg methylation.

Barnacle inspired strategy combined with solvent exchange for enhancing wet adhesion of hydrogels to promote seawater-immersed wound healing.

Hydrogels are promising materials for wound protection, but in wet, or underwater environments, the hydration layer and swelling of hydrogels can seriously reduce adhesion and limit their application. In this study, inspired by the structural characteristics of strong barnacle wet adhesion and combined with solvent exchange, a robust wet adhesive hydrogel (CP-Gel) based on chitosan and 2-phenoxyethyl acrylate was obtained by breaking the hydration layer and resisting swelling. As a result, CP-Gel exhibited strong wet adhesion to various interfaces even underwater, adapted to joint movement and skin twisting, resisted sustained rushing water, and sealed damaged organs.

Group arts therapies for patients with schizophrenia: a protocol of systematic review and meta-analysis.

Introduction: Schizophrenia, a chronic mental problem, significantly impacts cognition, emotion and social functioning. Conventional pharmacotherapy faces challenges including numerous side effects, low adherence to medication and substantial costs. In this context, group arts therapies (GATs) emerge as a promising complementary approach for symptom alleviation in schizophrenia patients.

The role of arts therapies in mitigating Sleep Initiation and Maintenance Disorders: a systematic review.

Introduction: Arts therapies offer effective non-pharmacological intervention for Sleep Initiation and Maintenance Disorders (SIMDs), encompassing both passive and active modalities. This review assesses their effectiveness and ethical considerations, focusing on music therapy, meditation, and Tai Chi.

Methods: Following PRISMA guidelines, a detailed search across PubMed, the Cochrane Library, Web of Science, and CNKI identified 17 relevant RCTs.

A Zn-MOF-GOx-based cascade nanoreactor promotes diabetic infected wound healing by NO release and microenvironment regulation.

Diabetic wound healing is a great clinical challenge due to the microenvironment of hyperglycemia and high pH value, bacterial infection and persistent inflammation. Here, we develop a cascade nanoreactor hydrogel (Arg@Zn-MOF-GOx Gel, AZG-Gel) with arginine (Arg) loaded Zinc metal organic framework (Zn-MOF) and glucose oxidase (GOx) based on chondroitin sulfate (CS) and Pluronic (F127) to accelerate diabetic infected wound healing. GOx in AZG-Gel was triggered by hyperglycemic environment to reduce local glucose and pH, and simultaneously produced hydrogen peroxide (HO) to enable Arg-to release nitric oxide (NO) for inflammation regulation, providing a suitable microenvironment for wound healing.

α7nAChR Activation Combined with Endothelial Progenitor Cell Transplantation Attenuates Lung Injury in Diabetic Rats with Sepsis through the NF-κB Pathway.

Chronic diabetes mellitus compromises the vascular system, which causes organ injury, including in the lung. Due to the strong compensatory ability of the lung, patients always exhibit subclinical symptoms. Once sepsis occurs, the degree of lung injury is more severe under hyperglycemic conditions.

Twelfth thoracic vertebra erector spinae plane block for postoperative analgesia and early recovery after lumbar spine surgery in elderly patients: a single-blind randomized controlled trial.

Background: Severe pain after lumbar spine surgery can delay recovery in elderly patients. We explored the efficacy of T12 erector spinal plane block (ESPB) in elderly patients who underwent lumbar spine surgery.

Methods: A total of 230 patients undergoing lumbar spine surgery were divided and randomly allocated to ultrasound-guided ESPB (n = 115) and control (n = 115) groups.

Insights into chromium removal mechanism by Ca-based sorbents from flue gas.

Chromium is a typical toxic pollution in sewage sludge incineration flue gas. Cr removal from flue gas is a challenge due to the high toxicity and valence variability of chromium. Ca-based sorbents, including CG-CaO, CA-CaO, and CCi-CaO, were developed for Cr capture by calcining calcium D-gluconate monohydrate, calcium acetate hydrate, and calcium citrate tetrahydrate, respectively.

Flexible coaxial composite fiber based on carbon nanotube and thermochromic particles for multifunctional sensor and wearable electronics.

Fibrous sensors are of interest in the fields of human activity, health monitoring and human-computer interactions due to their ability to measure human activity signals such as temperature and pressure. Although many different structures and conductive materials exist for fibrous sensors, the design and fabrication of fibrous multifunctional sensors still pose significant challenges. Here, we have designed a fibrous multifunctional sensor based on a wet-spinning three-layer coaxial fiber that exhibits a GF value of up to 45.

Meta-analysis of acupuncture combined with paroxetine in the treatment of depression.

Objective: To systematically evaluate the clinical efficacy of acupuncture combined with paroxetine in the treatment of depression.

Methods: The research literature on the treatment of depression with acupuncture and moxibustion combined with paroxetine was collected using keywords in PubMed, Embase, Web of Science, Cochrane Library, CNKI, World Wide Web, Chinese Biomedical Literature and other public publication databases. Collaborative screening of literature was performed according to pre-established inclusion and exclusion criteria.

mA-Mediated PPARA Translational Suppression Contributes to Corticosterone-Induced Visceral Fat Deposition in Chickens.

Excess fat deposition in broilers leads to great economic losses and is harmful to consumers' health. Chronic stress in the life cycle of chickens could be an important trigger. However, the underlying mechanisms are still unclear.

A Novel Image Encryption Algorithm Based on Improved Arnold Transform and Chaotic Pulse-Coupled Neural Network.

Information security has become a focal topic in the information and digital age. How to realize secure transmission and the secure storage of image data is a major research focus of information security. Aiming at this hot topic, in order to improve the security of image data transmission, this paper proposes an image encryption algorithm based on improved Arnold transform and a chaotic pulse-coupled neural network.

A Scientometric Visualization Analysis for Molecular Mechanisms of Substance Abuse and Its Neurotoxicity From 1997 to 2021.

Substance abuse has become a global problem due to drug-induced addiction and neurotoxicity, which causes a huge physical, social, and financial burden. Various kinds of drugs can hijack the users'/abusers' behavior and associated neurocircuitry. To summarize recent scientific advances on drug abuse, we reviewed relevant publications to analyze research progress and such trends through bibliometric ways.

Efficacy of acupuncture at ghost points combined with fluoxetine in treating depression: A randomized study.

Background: Depression affects more than 350 million people worldwide. In China, 4.2% (54 million people) of the total population suffers from depression.