Publications by authors named "Aihong Wei"
It was reported that the Wnt/β-catenin pathway is involved in the regulation of aerobic glycolysis and that brain glycolytic dysfunction results in the development of Alzheimer's disease (AD). Icariin (ICA), an active component extracted from Epimedii Folium, has been reported to produce neuroprotective effects in multiple models of AD, but its underlying mechanism remains to be fully described. We aimed to investigate the protective effects of ICA on animal and cell models of AD and confirm whether the Wnt/β-catenin pathway has functions in the neuroprotective function of ICA.
View Article and Find Full Text PDFObjective: To investigate the mechanism of RNA-binding protein hnRNP A1 in mouse hippocampal neurons (HT22) on glycolysis.
Methods: RIP and CLIP-qPCR were performed by HT22 to observe the mechanism of hnRNP A1 regulating the expression of key proteins in glycolysis. The RNA binding domain of hnRNP A1 protein in HT22 was inhibited by VPC-80051, and the effect of hnRNP A1 on glycolysis of HT22 was observed.
Article Synopsis
- Large-scale green tides from Ulva prolifera significantly harm marine environments, ecosystems, and local economies, primarily driven by eutrophication.
- Modeling is more effective than traditional survey methods for understanding the relationship between land nutrient loads and green tide outbreaks.
- In a study along the Jiangsu coast, changes in nitrogen and phosphorus levels due to land-based inputs were found to directly impact U. prolifera blooms, suggesting that managing nutrient loads is crucial for preventing future outbreaks.
[Compound huangdai tablet as induction therapy for 193 patients with acute promyelocytic leukemia].
Zhonghua Xue Ye Xue Za Zhi
July 2009
Objective: To report the results of curative and adverse effects of compound huangdai tablet (CHDT) as induction therapy for 193 patients with acute promyelocytic leukemia (APL).
Methods: CHDT was administered 1.25 g orally three times a day after meal for three days, then the dosage was gradually increased to 7.