Publications by authors named "Aiguo Lv"
Article Synopsis
- The study aimed to compare the 24-hour intraocular pressure (IOP) fluctuations between patients newly diagnosed with ocular hypertension (OHT) and primary open-angle glaucoma (POAG).
- It involved monitoring IOP every 2 hours over a full day, finding that POAG patients had a steeper increase in IOP during the daytime and a faster decrease at night compared to OHT patients.
- The findings suggest that larger IOP fluctuations might indicate a higher risk of POAG, but the study has limitations, including relying on a single 24-hour measurement and needing further research for confirmation.
Prcis: The combination of surgical peripheral iridectomy, goniosynechialysis, and goniotomy is a safe and effective surgical approach for advanced primary angle closure glaucoma without cataract.
Purpose: To evaluate the efficacy and safety of surgical peripheral iridectomy (SPI), goniosynechialysis (GSL), and goniotomy (GT) in advanced primary angle closure glaucoma (PACG) eyes without cataract.
Patients And Methods: A prospective multicenter observational study was performed for patients who underwent combined SPI, GSL, and GT for advanced PACG without cataract.
Article Synopsis
- The study examines the effectiveness of a combined eye surgery (phacoemulsification, goniosynechialysis, and goniotomy) for treating primary angle closure glaucoma in patients with cataracts, noting that success is not influenced by the severity of peripheral anterior synechiae.
- It involved 304 eyes from 283 patients over around 12.5 months, showing a significant reduction in intraocular pressure (IOP) post-surgery across all severity groups, with no notable differences in success rates.
- Although more severe peripheral anterior synechiae (270°≤PAS<360°) experienced increased instances of complications like hyphema, the overall results indicated that the combined procedure is effective regardless of PAS extent
Phacogoniotomy versus phacotrabeculectomy for advanced primary angle-closure glaucoma with cataract: A randomized non-inferiority trial.
Asia Pac J Ophthalmol (Phila)
February 2024
Purpose: To investigate the effectiveness and safety of phacogoniotomy versus phacotrabeculectomy (PVP) among patients with advanced primary angle-closure glaucoma (PACG) and cataracts.
Design: Multicenter, randomized controlled, non-inferiority trial.
Methods: A total of 124 patients (124 eyes) with advanced PACG and cataracts were enrolled, with 65 in the phacogoniotomy group and 59 in the phacotrabeculectomy group.
Purpose: To compare the efficacy of morning and evening latanoprost/timolol fixed-combination (LTFC) dosing in patients with primary open-angle glaucoma (POAG) and ocular hypertension.
Methods: In this double-blind, randomized clinical trial, 63 untreated Chinese patients with POAG and ocular hypertension were enrolled. All patients received LTFC and were randomized (1:1) to group 1, morning (8 AM) dosing, or group 2, evening (8 PM) dosing.
Prcis: Goniotomy (GT) is an alternative surgery for patients with prior failed surgery for glaucoma.
Purpose: To evaluate the efficacy and safety of GT in patients with prior failed surgery for glaucoma.
Materials And Methods: A prospective, observational multicentered study was performed for patients who underwent GT with prior single or multiple surgery for glaucoma.
Purpose: To evaluate the intraocular pressure (IOP)-lowering effect of the combination of phacoemulsification with intraocular lens implantation (PEI), goniosynechialysis (GSL), and goniotomy (GT) in eyes of advanced primary angle-closure glaucoma (PACG) with cataract.
Design: Multicenter observational study.
Methods: We enrolled 83 eyes of 83 patients with advanced PACG who received combined PEI+GSL+GT at 8 ophthalmic institutes.
Introduction: Primary angle-closure glaucoma (PACG) is a major subtype of glaucoma that accounts for most bilateral glaucoma-related blindness globally. Filtering surgery is a conventional strategy for PACG, yet it has a long learning curve and undesirable disastrous complications. Minimally invasive glaucoma surgery (MIGS) plays an increasing role in the management of glaucoma due to its safer and faster recovery profile; cataract surgery-based MIGS is the most commonly performed such procedure in PACG.
View Article and Find Full Text PDFIntroduction: Primary angle-closure glaucoma (PACG) has a high prevalence and blinding rate across Asia. The first-line treatment of PACG is surgery, and phacotrabeculectomy remains the mainstream surgery for advanced PACG. However, it may cause vision-threatening complications with long learning curve.
View Article and Find Full Text PDFBy 2040, ~100 million people will have glaucoma. To date, there are a lack of high-efficiency glaucoma diagnostic tools based on visual fields (VFs). Herein, we develop and evaluate the performance of 'iGlaucoma', a smartphone application-based deep learning system (DLS) in detecting glaucomatous VF changes.
View Article and Find Full Text PDFAims: To study the risk factors associated with blindness after treatment of acute primary angle closure (APAC), and to identify the critical time window to decrease rate of blindness.
Methods: In this multicentre retrospective case series, 1030 consecutive subjects (1164 eyes) with APAC in China were recruited. The rates of blindness were analysed up to 3 months after treatment of APAC.