Symptomatic Zika Virus Infection in Infants, Children, and Adolescents Living in Puerto Rico.

Importance: Little information is available regarding Zika virus (ZIKV) infection in children.

Objective: To describe patients younger than 18 years who were infected with ZIKV and were enrolled in the Sentinel Enhanced Dengue and Acute Febrile Illness Surveillance System (SEDSS).

Design, Setting, And Participants: Children infected with ZIKV with 7 or fewer days of fever or emancipated minors aged 14 to 17 years with a generalized maculopapular rash, arthritis or arthralgia, or nonpurulent conjunctivitis were eligible for enrollment on or before December 31, 2016, in Puerto Rico.

Dengue deaths in Puerto Rico: lessons learned from the 2007 epidemic.

Background: The incidence and severity of dengue in Latin America has increased substantially in recent decades and data from Puerto Rico suggests an increase in severe cases. Successful clinical management of severe dengue requires early recognition and supportive care.

Methods: Fatal cases were identified among suspected dengue cases reported to two disease surveillance systems and from death certificates.