Sensing Thermophoretic Forces by Nanoplasmonic Actuators with Interferometric Scattering Readout.

Noble metal nanoparticles (NPs) represent nanoscale, optically addressable heat sources whose temperature gradients give rise to thermophoretic forces that can act back on the NPs. Herein we investigate 20 nm Ag NPs bound via molecular tethers to a 20 nm thin Au film as nanoplasmonic actuators that generate a local temperature gradient and simultaneously act as optical sensors of forces that induce their displacement from their equilibrium position. Forces of sufficient magnitude to affect the NP-film distance modulate the interferometric scattering (iSCAT) signal of the individual NPs and become detectable due to the distance-dependent damping of the NP scattering in the vicinity of the metal film.

Two-color interferometric scattering (iSCAT) microscopy reveals structural dynamics in discrete plasmonic molecules.

Plasmonic molecules are discrete assemblies of noble metal nanoparticles (NPs) that are of interest as transducers in optical nanosensors. So far, NPs with diameters of ∼40 nm have been the preferred building blocks for plasmonic molecules intended as optical single molecule sensors due to difficulties associated with detecting smaller NPs through elastic scattering in conventional darkfield microscopy. Here, we apply 405 nm, 445 nm two-color interferometric scattering (iSCAT) microscopy to characterize polyethylene glycol (PEG) tethered dimers of 10 nm and 20 nm Ag NPs and their monomers.