Healthy lifestyle associated with dynamic progression of type 2 diabetes: A multi-state analysis of a prospective cohort.

Background: Although the association of a healthy lifestyle with type 2 diabetes (T2D) has been extensively studied, its impact on the dynamic trajectory, including progression, onset and prognosis, of T2D has not been investigated.

Methods: Using data from the UK Biobank, 461 168 participants without diabetes or diabetes-related events were included. We incorporated four lifestyle factors to construct the healthy lifestyle score (HLS).

Effects of Ambient Air Pollution on Precocious Puberty: A Case-Crossover Analysis in Nanjing, China.

Background: Ambient air pollution is closely related to a variety of health outcomes. Few studies have focused on the correlations between air pollution exposure and children's sexual development. In this study, we investigated the potential effects of exposure to air pollution on precocious puberty among children using real-world evidence.

Higher-Order Mode Suppression in Antiresonant Nodeless Hollow-Core Fibers.

Negative curvature hollow-core fibers (NC-HCFs) are useful as gas sensors. We numerically analyze the single-mode performance of NC-HCFs. Both single-ring NC-HCFs and nested antiresonant fibers (NANFs) are investigated.

Intensity and temporal noise characteristics in femtosecond optical parametric amplifiers.

We characterize the relative intensity noise (RIN) and relative timing jitter (RTJ) between the signal and pump pulses of optical parametric amplifiers (OPAs) seeded by three different seed sources. Compared to a white-light continuum (WLC) seeded- and an optical parametric generator (OPG) seeded OPA, the narrowband CW seeded OPA exhibits the lowest root-mean-square (RMS) RIN and RTJ of 0.79% and 0.