Analysis of the relationship between the quality of antenatal care examinations and the incidence of preterm birth and low birth weight.

Background: Antenatal care (ANC) plays a crucial role in ensuring maternal and child safety and reducing adverse delivery outcomes. This study aimed to analyze the association between the quality of ANC and the occurrence of preterm birth and low birth weight in a sample of the population from 16 regions in 8 provinces in China.

Methods: Data from all closed cases of pregnant women and newborns reported in the Maternal and Child Health Monitoring System from January 1, 2018, to December 31, 2018, in 16 monitoring regions across 8 provinces in China were collected and included in the analysis, resulting in a total of 49,084 pregnant women and 49,026 newborns.

Effects of feeding patterns during the first 6 months on weight development of infants ages 0-12 months: a longitudinal study.

The purpose of this study was to investigate the effect of feeding patterns during the first 6 months on weight development of infants ages 0-12 months. Using monitoring data from the Maternal and Child Health Project conducted by the National Center for Women and Children's Health of the Chinese Center for Disease Control and Prevention from September 2015 to June 2019, we categorized feeding patterns during the first 6 months as exclusive breastfeeding, formula feeding, or mixed feeding. We calculated weight-for-age Z scores (WAZ) according to the World Health Organization's (WHO) 2006 Child Growth Standard using WHO Anthro version 3.

Prevalence and influencing factors of anemia among pregnant women across first, second and third trimesters of pregnancy in monitoring areas, from 2016 to 2020: a population-based multi-center cohort study.

Objective: To assess the prevalence of anemia among pregnant women across their entire pregnancy and the factors affecting it in the monitoring areas.

Methods: A total of 108,351 pregnant women who received antenatal health care and delivered from January 1, 2016 to December 31, 2020 in 15 monitoring counties of 8 provinces in the Maternal and Newborn Health Monitoring Program (MNHMP) of National Center for Women and Children's Health (NCWCH) were selected as the study subjects. The anemia status among the subjects across their first, second and third trimester of pregnancy and the influencing factors were analyzed.

Exploration of the preterm birth risk-related heat event thresholds for pregnant women: a population-based cohort study in China.

Background: Heat events increase the risk of preterm birth (PTB), and identifying the risk-related event thresholds contributes to developing early warning system for pregnant women and guiding their public health response. However, the event thresholds that cause the risk remain unclear. We aimed to investigate the effects of heat events defined with different intensities and durations on PTB throughout pregnancy, and to determine thresholds for the high-risk heat events.

c-Met is a chimeric antigen receptor T-cell target for treating recurrent nasopharyngeal carcinoma.

Background Aims: Radiation therapy is the standard treatment for patients with nasopharyngeal carcinoma (NPC), but relapse occurs in 10% to 20% of patients. The treatment of recurrent nasopharyngeal carcinoma (rNPC) remains challenging. Chimeric antigen receptors (CAR)-T-cell therapy has achieved good outcomes in the treatment of leukemia and seems to be a promising therapeutic strategy for solid tumors.

Effects of gestational ambient extreme temperature exposures on the risk of preterm birth in China: A sibling-matched study based on a multi-center prospective cohort.

Background: Previous epidemiological findings on extreme temperature and preterm birth (PTB) were heterogeneous, especially for extreme cold exposure. Measured and unmeasured individual-level factors such as genetic factors or lifecourse exposures may constitute important contributors but have not been addressed.

Objectives: We aimed to examine the association of gestational heat and cold exposure with PTB using a novel sibling-matched study.

Relationship between Maternal Postpartum Intention to Breastfeed and Actual Breastfeeding Duration - Four Provinces, China, 2015-2017.

What Is Already Known About This Topic?: Several studies have reported that maternal antenatal intention to breastfeed is a strong predictor of actual breastfeeding duration. However, little research has investigated whether maternal postpartum intention also extends breastfeeding duration.

What Is Added By This Report?: Maternal postpartum intention to breastfeed was a protective factor for extending actual breastfeeding duration after controlling potential confounders.

The Distribution of Pregnant Women with Different Pregnancy Risks - 4 Cities, China, 2019.

Summary:

Unlabelled: Based on different pregnancy risk levels, the implementation of the "Five-Color Management" for pregnant women can prevent adverse pregnancy outcomes and ensure the safety of mothers and infants.

Unlabelled:

Unlabelled: The proportions of being multipara and of advanced maternal age in the 4 cities (Beijing, Chengdu, Shenzhen, and Wuhan) were 47.4% and 13.

Incidence and Risk Factors of Hypertensive Disorders of Pregnancy - 8 Provinces, China, 2014-2018.

As a major cause of maternal and neonatal mortality and morbidity, hypertensive disorders of pregnancy (HDP) are a global public health problem affecting maternal and children's health. The incidence of HDP was 6.40% among 277,632 pregnant women.

Current status of antenatal care of pregnant women-8 provinces in China, 2018.

Background: Antenatal care (ANC) played a crucial role in ensuring maternal and child safety and reducing the risk of complications, disability, and death in mothers and their infants. The objective of this study was to evaluate the current status of ANC emphasizing the number, timing, and content of examinations on a national scale.

Methods: The data was collected from maternal and newborn's health monitoring system at 8 provinces in China.

The Impact of New Adjustments to the Family Planning Policy on the Number of Live Births in Four Developed Urban Areas - China, 2013-2019.

Due to shifting circumstances in China, the government has adjusted the child-bearing policy to allow couples to have a second child. This has affected the total number of live births, especially in more developed urban areas. The total number of live births in the 4 monitoring cities including Chengdu, Wuhan, Shenzhen, and Beijing during 2014-2019 increased by 33.

Reference ranges and trajectories for blood pressure in pregnancy: findings from a follow-up study based on China Maternal and Newborn's Health Monitoring System.

: This study aimed to establish normal blood pressure reference ranges across gestation and maternal characteristics.: We conducted a follow-up study including 29,200 Chinese normal pregnant women. Multilevel restrictive cubic spline models were used to calculate normal blood pressure reference ranges among all population and stratified groups.

Prevalence and Risk Factors of Anemia of Pregnant Women - 6 Provinces in China, 2014-2018.

Anemia during pregnancy is a global public health problem affecting both maternal and children's health. The "National Nutrition Plan (2017-2030)" and "Healthy China Action (2019-2030)" issued by the State Council of China in 2017 and 2019, respectively, specified nutrition targets: by 2030, the anemia rate in pregnant women should be reduced to less than 10%. The anemia prevalence of pregnant women reported by the Chinese Nutrition and Health Surveillance in 2006 and 2010-2012 was 42.

Gestational Weight Gain Charts by Gestational Age and Body Mass Index for Chinese Women: A Population-Based Follow-up Study.

Background: Establishment of an unbiased association between gestational weight gain (GWG) and perinatal health is urgently needed in China, which has the largest population in the world. Our study aimed to create weight-gain-for-gestational-age charts using early pregnancy body mass index (BMI) to present selected percentiles of GWG in China.

Methods: A population-based follow-up study was conducted based on the Maternal and Newborn Health Monitoring System, which recruited 132,835 pregnant women between October 2013 and September 2016 in 12 districts/counties of 6 provinces in China.

Blood pressure in early and mid-pregnancy and the risk of small-for-gestational-age birth: findings of a large cohort study in China.

The influences of blood pressure in early to mid-pregnancy on the risk of small-for-gestational-age (SGA) birth are not clear. Our objective was to examine the associations of the blood pressure levels at 10 and 18 gestational weeks with the risk of SGA birth. Data were obtained from the Chinese Maternal and Newborn's Health Monitoring System (MNHMS).

Attendance at prenatal care and adverse birth outcomes in China: A follow-up study based on Maternal and Newborn's Health Monitoring System.

Objective: to evaluate the independent association between attendance at prenatal care and adverse birth outcomes in China, measured either as the occurrence of preterm birth or low birth weight.

Design: a follow-up study.

Setting: the data was collected from maternal and newborn's health monitoring system at 6 provinces in China.

Dynamics of DNA Squeezed Inside a Nanochannel via a Sliding Gasket.

We use Brownian dynamics (BD) simulation of a coarse-grained (CG) bead-spring model of DNA to study the nonequilibrim dynamics of a single DNA molecule confined inside a rectangular nanochannel being squeezed with a sliding gasket piston or "nanodozer". From our simulations we extract the nonequilibrim density profile c ( x , t ) of the squeezed molecule along the channel axis (-coordinate) and then analyze the non-equilibrium profile using a recently introduced phenomenological Nonlinear Partial Differential Equation (NPDE) model. Since the NPDE approach also fits the experimental results well and is numerically efficient to implement, the combined BD + NPDE methods can be a powerful approach to analyze details of the confined molecular dynamics.

Rate of gestational weight gain and preterm birth in relation to prepregnancy body mass indices and trimester: a follow-up study in China.

Background: To evaluate the association between rate of gestational weight gain and preterm birth varying prepregnancy body mass indices and trimester.

Methods: Data from Maternal and Newborn's Health Monitoring System on 17475 pregnant women who delivered live singletons at ≥ 28 weeks of gestation between October 2013 and September 2014 from 12 districts/counties of 6 provinces in China and started prenatal care at ≤ 12 weeks of gestation was analyzed. Gestational weight gain was categorized by rate of weight gain during the 2(nd) and 3(rd) trimester, based on the 2009 Institute of Medicine guidelines.

Semiflexible macromolecules in quasi-one-dimensional confinement: Discrete versus continuous bond angles.

The conformations of semiflexible polymers in two dimensions confined in a strip of width D are studied by computer simulations, investigating two different models for the mechanism by which chain stiffness is realized. One model (studied by molecular dynamics) is a bead-spring model in the continuum, where stiffness is controlled by a bond angle potential allowing for arbitrary bond angles. The other model (studied by Monte Carlo) is a self-avoiding walk chain on the square lattice, where only discrete bond angles (0° and ±90°) are possible, and the bond angle potential then controls the density of kinks along the chain contour.

A matched case-control study of preterm birth in one hospital in Beijing, China.

Background: Preterm birth is an unresolved global health issue. The etiologies of preterm birth are complex and multifactorial. To examine risk factors related to preterm birth, a matched case-control study was conducted in a hospital in Beijing, China where little data on preterm birth have been published in the scientific literature.

Conformations, transverse fluctuations, and crossover dynamics of a semi-flexible chain in two dimensions.

We present a unified scaling description for the dynamics of monomers of a semiflexible chain under good solvent condition in the free draining limit. We consider both the cases where the contour length L is comparable to the persistence length ℓ(p) and the case L ≫ ℓ(p). Our theory captures the early time monomer dynamics of a stiff chain characterized by t(3/4) dependence for the mean square displacement of the monomers, but predicts a first crossover to the Rouse regime of t(2ν/1 + 2ν) for τ¹ ~ ℓ(p)³, and a second crossover to the purely diffusive dynamics for the entire chain at τ2 ∼ L(5/2).

Effects of Cd(II) and cu(II) on microbial characteristics in 2-chlorophenol-degradation anaerobic bioreactors.

The effects of Cd2+ and Cu2+ at 300 mg/L on anaerobic microbial communities that degrade 2-cholorophenol (2-CP) were examined. Based on the polymerase chain reaction (PCR) of 16S rDNA, bacterial community diversity and archaeal community structure were analyzed with denaturing gradient gel electrophoresis (DGGE) and cloning, respectively. Degradation capabilities of the anaerobic microbial community were drastically abated and the degradation efficiency of 2-CP was reduced to 60% after shock by Cu2+ and Cd2+, respectively.

Association of the lipoprotein lipase gene T+495G polymorphism with central obesity and serum lipids in a twin study.

Purpose: The lipoprotein lipase (LPL) gene polymorphism is possibly involved in the pathophysiology of central obesity and dyslipidemia. The aim of this study was to investigate the association of LPL gene T+495G polymorphism with central obesity and serum lipids.

Methods: A total of 961 adult twin pairs were enrolled from the program of Chinese Twin Registry, between 2001 and 2002.