Publications by authors named "Ai-yun Yuan"
[Association of TLR3-1377C/T gene polymorphisms and expression with susceptibility to enterovirus 71 encephalitis in children].
Zhongguo Dang Dai Er Ke Za Zhi
January 2017
Article Synopsis
- The study explored the relationship between TLR3 gene polymorphisms and susceptibility to enterovirus 71 (EV71) encephalitis in children, comparing those with and without encephalitis.
- While genotype frequencies for TLR3-1377C/T were similar between groups, both encephalitis and non-encephalitis patients showed higher serum TLR3 levels than controls, with non-encephalitis patients having the highest levels.
- The encephalitis group had a greater EV71 viral load, and children over 1 year had higher TLR3 levels compared to younger children within the same group, indicating age-related differences in immune response.
[Autistic spectrum disorders associated with chromosome Mar15q11.2: a case report].
Zhongguo Dang Dai Er Ke Za Zhi
March 2015
[Differences of apoptotic-regulating gene expression in the hippocampus in rats with different ages after status convulsion].
Zhongguo Dang Dai Er Ke Za Zhi
May 2011
Objective: To explore the molecular mechanism of brain protection against convulsive brain damage in premature brains by observing the changes of apoptotic-regulating genes of bcl-2 and c-Jun expression in the hippocampus in Wistar rats with different ages after status convulsion (SC).
Methods: SC was induced in infant Wistar rats (IRs) and adult Wistar rats (ARs) by intraperitoneal injection of lithium-pilocarpine. The rats were sacrificed at 3 hrs, 6 hrs, 12 hrs, 1 day, 3 days and 7 days after SC (n=8).
[Effect of duration of convulsion state on neuronal apoptosis and early apoptotic events in hippocampus of rats].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
June 2007
Objective: To explore the influence of duration of convulsion state (SC) on neuronal apoptosis, mitochondrial membrane potential (Deltapsim) and cytochrome C (cyt C) release in hippocampus in Wistar rats after SC.
Methods: SC lasting for 30 minutes or 3 hours was induced by intraperitoneal injection of lithium chloride and pilocarpine. Rats were sacrificed at 3, 6, 12 hours and on 1 day after 30 minutes SC and at 3, 6 hours and on 1 day after 3 hours SC.