[Effects of FAK expression level on proliferation and motility of colorectal carcinoma cells].

Aim: To investigate the effect of siRNA targeting FAK gene on proliferation and motility of colorectal cancer.

Methods: Recombinant plasmids that produced siRNAs targeting FAK were designed and cloned, then transfected into Caco-2 cells. The changes of FAK expression levels were examined by RT-PCR and immunocytochemistry.