Synopsis of recent research by authors named "Ai-ming Yu"
- Ai-Ming Yu's recent research primarily focuses on the development and enhancement of RNA-based therapeutics, including the engineering of small interfering RNA (siRNA) and microRNA (miRNA) agents to improve gene regulation and combat diseases like cancer.
- His studies highlight significant advances in nanopore sequencing technologies aimed at increasing accuracy in basecalling for therapeutic RNA quality control, addressing challenges presented by nucleotide modifications that can yield misleading results in sequencing data.
- Additionally, Yu's work emphasizes understanding drug resistance mechanisms in cancer treatment, particularly how efflux ABC transporters and molecular targets can be manipulated to enhance the efficacy of therapies like Olaparib in resistant cancer cells.
