The Main Failure Modes of Hot-Work Die Steel and the Development Status of Traditional Strengthening Methods and Nano-Strengthening Technology.

As an important part of die steels, hot-work die steels are mainly used to manufacture molds made of solid metal or high-temperature liquid metal from heating to recrystallization temperature. In view of the requirements for mechanical properties and service life for hot-work die steel, it is conducive to improve the thermal fatigue resistance, wear resistance, and oxidation resistance of hot work die steel. In this review, the main failure modes of hot-work die steel were analyzed.

Methylation enables the use of fluorine-free ether electrolytes in high-voltage lithium metal batteries.

Lithium metal batteries represent a promising technology for next-generation energy storage, but they still suffer from poor cycle life due to lithium dendrite formation and cathode cracking. Fluorinated solvents can improve battery longevity by improving LiF content in the solid-electrolyte interphase; however, the high cost and environmental concerns of fluorinated solvents limit battery viability. Here we designed a series of fluorine-free solvents through the methylation of 1,2-dimethoxyethane, which promotes inorganic LiF-rich interphase formation through anion reduction and achieves high oxidation stability.

[Detection, Generation, and Control of Disinfection By-products of Reclaimed Water].

At the time when water resources are in short supply,wastewater recycling is both an important environmental protection strategy and also a resource strategy. Disinfection is essential to ensure the biological safety of reclaimed wastewater by killing pathogens and preventing the spread of waterborne diseases. However,the disinfection process could inevitably produce toxic disinfection byproducts(DBPs)due to the reaction between the disinfectants and wastewater organic matters.

High voltage electrolytes for lithium-ion batteries with micro-sized silicon anodes.

Micro-sized silicon anodes can significantly increase the energy density of lithium-ion batteries with low cost. However, the large silicon volume changes during cycling cause cracks for both organic-inorganic interphases and silicon particles. The liquid electrolytes further penetrate the cracked silicon particles and reform the interphases, resulting in huge electrode swelling and quick capacity decay.

Revealing the Anion-Solvent Interaction for Ultralow Temperature Lithium Metal Batteries.

Anion solvation in electrolytes can largely change the electrochemical performance of the electrolytes, yet has been rarely investigated. Herein, three anions of bis(trifluoromethanesulfonyl)imide (TFSI), bis(fluorosulfonyl)imide (FSI), and derived asymmetric (fluorosulfonyl)(trifluoro-methanesulfonyl)imide (FTFSI) are systematically examined in a weakly Li cation solvating solvent of bis(3-fluoropropyl)ether (BFPE). In-situ liquid secondary ion mass spectrometry demonstrates that FTFSI and FSI anions are associated with BFPE solvent, while weak TFSI /BFPE cluster signals are detected.

Psittacosis caused severe community-acquired pneumonia accompanied by acute hypoxic respiratory failure: a multicenter retrospective cohort study from China.

Introduction: Psittacosis can cause severe community-acquired pneumonia (CAP). The clinical manifestations of psittacosis range from subclinical to fulminant psittacosis with multi-organ failure. It is essential to summarize the clinical characteristic of patients with severe psittacosis accompanied by acute hypoxic respiratory failure (AHRF).

Clinical guideline on magnetically controlled capsule gastroscopy (2021 edition).

With the development and generalization of endoscopic technology and screening, clinical application of magnetically controlled capsule gastroscopy (MCCG) has been increasing. In recent years, various types of MCCG are used globally. Therefore, establishing relevant guidelines on MCCG is of great significance.

Unraveling the evolution of dissolved organic matter in full-scale A/A/O wastewater treatment process using size exclusion chromatography with PARAFAC and nonnegative matrix factorization analysis.

Changes in spectral features and molecular weight (MW) of dissolved organic matter (DOM) along the A/A/O processes in eight full-scale wastewater treatment plants (WWTPs) were characterized using size exclusion chromatography with a diode array detector, a fluorescence detector and an organic carbon detector in tandem (SEC-DAD-FLD-OCD) as well as bulk water quality parameters. The parallel factor (PARAFAC) and the nonnegative matrix factorization (NMF) analyses have been effectively applied to the postprocessing of SEC-FLD fingerprints and SEC-OCD chromatograms, respectively. Individual SEC-FLD-PARAFAC or SEC-OCD-NMF components may span a broad range of MW, indicating that these SEC fractions within the same component were cognate and varied coherently across the dataset samples.

Changes of dissolved organic matter fractions and formation of oxidation byproducts during electrochemical treatment of landfill leachates: Development of spectroscopic indicators for process optimization.

Electrochemical oxidation (EO) is an attractive option for treatment of dissolved organic matter (DOM) in landfill leachate but concerns remain over the energy efficiency and formation of oxidation byproducts ClO and ClO. In this study, EO treatment of landfill leachates was carried out using representative active and nonactive anode materials, cell configurations and current densities. Size exclusion chromatograms coupled with 2D synchronous and asynchronous correlation analysis showed that the sensitivity of DOM fractions to EO degradation was dependent on the anode material.

Simultaneous determination of dissolved organic nitrogen, nitrite, nitrate and ammonia using size exclusion chromatography coupled with nitrogen detector.

Accurate quantification of dissolved organic nitrogen (DON) has been a challenge due to the cumulative analytical errors in the conventional method via subtracting dissolved inorganic nitrogen species (DIN) from total dissolved nitrogen (TDN). Size exclusion chromatography coupled with an organic nitrogen detector (SEC-OND) has been developed as a direct method for quantification and characterization of DON. However, the applications of SEC-OND method still subject to poor separations between DON and DIN species and unsatisfied N recoveries of macromolecules.

Unravelling relationships between fluorescence spectra, molecular weight distribution and hydrophobicity fraction of dissolved organic matter in municipal wastewater.

The characteristics of dissolved organic matter (DOM) in the influent and secondary effluent from 6 municipal wastewater treatment plants (WWTPs) were investigated with a size exclusion chromatogram (SEC) coupled with multiple detectors to simultaneously detect ultraviolet absorbance, fluorescence, dissolved organic carbon (DOC) and dissolved organic nitrogen (DON) as a function of molecular weight (MW). The SEC chromatograms showed that biopolymers (>6 kDa) and humic substances (0.5-6 kDa) comprised the significant fraction in the influent, while humic substances became the abundant proportion in the secondary effluent.

Hydrophobic Biodegradable Hyperbranched Copolymers with Excellent Marine Diatom Resistance.

As the utilization of degradable polymer coatings increased, the accompanying trade-off between good degradability and high-efficiency antidiatom adhesion due to their hydrophobic nature remains unresolved. The study presents a new hydrophobic surface-fragmenting coating consisting of degradable hyperbranched polymers (hereafter denoted as h-LLA) synthesized by reversible complexation-mediated copolymerization with isobornyl acrylate (IBOA) and divinyl-functional oligomeric poly(l-lactide) (OLLA-V), both derived from biomass, that exhibited superior resistance (∼0 cell mm) to marine diatom () attachment with higher OLLA content. The combined impact of the microscale hollow semisphere micelles that self-assembled degradable hyperbranched copolymers and hydrolysis-driven self-renewable surfaces following immersion in seawater may account for the remarkable resistance of h-LLA coatings against .

Immunomodulatory Effects of Walp. Polysaccharides on an Immunosuppression Model Induced by Cyclophosphamide.

Background: Walp. (Maca) has emerged as a functional plant food and traditional herb owing to its biological activities; Maca polysaccharides as an important active component of Maca have good immunomodulatory effect; however, studies on the immunomodulatory effect of Maca polysaccharides are mainly focused on macrophages; little attention has been devoted to the mechanisms and other immune cells. This study is aimed at investigating the immunomodulatory effects and mechanisms of Maca polysaccharides.

Endoscopic resection via antral submucosal tunneling for en bloc removal of tumors in the duodenal bulb.

To overcome difficulties in the removal of duodenal bulb lesions, especially those in anatomically challenging locations, we developed the endoscopic resection via antral submucosal tunneling (ERAST) technique. In this study, we evaluated the feasibility and safety of ERAST for the removal of superficial and subepithelial lesions in the duodenal bulb. This was a single-center retrospective study of 10 patients with lesions in the bulb.

The Correlation Between Mechanical Ventilation Duration, Pediatric Sequential Organ Failure Assessment Score, and Blood Lactate Level in Children in Pediatric Intensive Care.

Objective: This study aimed to investigate whether the ventilation duration for children undergoing invasive mechanical ventilation (IMV) in pediatric intensive care unit (PICU) is correlated with pediatric sequential organ failure (pSOFA) score, white blood cell (WBC) count, blood lactate level, and duration of fever.

Methods: Retrospectively reviewed that the medical records of patients who received IMV in the PICU of Jingzhou Central Hospital between January 2018 and December 2020. According to the duration of IMV in diagnosis-related groups, these patients were divided into two groups: group A, ventilation duration <96 h, and group B, ventilation duration ≥96 h.

Release and removal of algal organic matter during prechlorination and coagulation treatment of cyanobacteria-laden water: Are we on track?

A better understanding of the physicochemical properties and fate of algae-derived organic matter (AOM) in water treatments significantly benefits the control of algae-derived disinfection byprodcuts and process parameter optimization. In this study, we conducted a comprehensive investigation of the release and treatability of dissolved organic matter during prechlorination and postcoagulation treatments of cyanobacteria-laden source water via size-exclusion chromatography-tandem diode array detector, fluorescence detector and organic carbon detector. The results revealed that the allochthonous humic substances could protect algal cell membrane from damage during prechlorination at a low level of chlorine dose.

[Interventional effect of IL-17A on chronic obstructive pulmonary disease and its mechanism].

To investigate the intervention effects and mechanism of interleukin-17A (IL-17A) on chronic obstructive pulmonary disease (COPD). C57BL/6 mice were randomly divided into wild type blank control group, wild type COPD group and IL-7A knockout COPD group. Mice in wild type blank control group received no treatment, and mice in the other two groups were exposed to cigarette smoke to induce COPD (Cigarette: 1 cigarette / time, 4 times/day, 45 minutes/time; interval time: 1 hour; total intervention time: 90 days).

Contrasting Bonding Extremes in Two [Ge] Complexes: A Wadian Polyhedron ( = 2) versus a Hydrocarbon-like 2c-2e Polygermanide ( = 12).

[Nb(η-CHMe)] reacts with ethylenediamine (en) solutions of KGe in the presence of 18-crown-6 to give [(η-CHMe)NbHGe] () and [(η-CHMe)NbGeNb(η-CHMe)] () as their corresponding [K(18-crown-6)] salts. The crystalline solids are dark brown, air-sensitive, and sparingly soluble or insoluble in most solvents. The [K(18-crown-6)] salts of cluster ions and have been characterized by energy-dispersive X-ray (EDX) analysis, NMR studies, single-crystal X-ray diffraction, and electrospray ionization time-of-flight (ESI-TOF) mass spectrometry studies.

Substrate competition and microbial function in sulfate-reducing internal circulation anaerobic reactor in the presence of nitrate.

Nitrate and sulfate often coexist in organic wastewater. In this study, an internal circulation anaerobic reactor was conducted to investigate the impact of nitrate on sulfate reduction. The results showed that sulfate reduction rate dropped from 78.

Rapid determination of trace haloacetic acids in water and wastewater using non-suppressed ion chromatography with electrospray ionization-tandem mass spectrometry.

A simple and rapid method employing non-suppressed ion chromatography with electrospray ionization tandem mass spectrometry has been developed for the direct determination of trace-level haloacetic acids (HAAs) in water samples. Using 70/30 (v/v) acetonitrile/1 M aqueous methylamine as the mobile phase, three IC columns - AS16, AS18 and AS24 from Thermo-Scientific - were tested, respectively, with the AS16 column exhibiting the best overall performance with respect to resolution and retention time. To assess the effects of mobile phase composition on retention time of HAAs, the AS16 column was further tested using (i) different proportions of acetonitrile to aqueous methylamine, (ii) different proportions of acetonitrile to aqueous solution at fixed methylamine concentrations, and (iii) different concentrations of methylamine at fixed proportions of acetonitrile to aqueous solution.

A three serum miRNA panel as diagnostic biomarkers of radiotherapy-related metastasis in non-small cell lung cancer.

Serum microRNAs (miRNAs) have been implicated as noninvasive biomarkers for lung cancer diagnosis. However, there are no sensitive and specific biomarkers for the detection of radiotherapy-related non-small cell lung cancer (NSCLC) metastasis. The present study aimed to investigate the role of three serum miRNAs, namely miRNA (miR)-130a, miR-25 and miR-191*, in diagnosing NSCLC, and their biological functions in radiation-mediated development of metastatic properties in A549 cells.