Publications by authors named "Ai-li Gou"

Background: After being polio free for more than 10 years, an outbreak following importation of wild poliovirus (WPV) was confirmed in Xinjiang Uygur Autonomous Region, China, in 2011.

Methods: A cross-sectional study was conducted prior to supplementary immunization activities (SIAs), immediately after the confirmation of the WPV outbreak. In selected prefectures, participants aged ≤ 60 years old who visited hospitals at county-level or above to have their blood drawn for reasons not related to the study, were invited to participate in our study.

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Background: The last case of infection with wild-type poliovirus indigenous to China was reported in 1994, and China was certified as a poliomyelitis-free region in 2000. In 2011, an outbreak of infection with imported wild-type poliovirus occurred in the province of Xinjiang.

Methods: We conducted an investigation to guide the response to the outbreak, performed sequence analysis of the poliovirus type 1 capsid protein VP1 to determine the source, and carried out serologic and coverage surveys to assess the risk of viral propagation.

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Synopsis of recent research by authors named "Ai-li Gou"

  • - Ai-Li Gou has focused on the resurgence of poliomyelitis in Xinjiang, China, specifically addressing outbreaks following the importation of wild poliovirus, highlighting the importance of ongoing surveillance and vaccination efforts.
  • - Her research includes comprehensive serological studies to measure the presence of polio antibodies in the population, conducted prior to supplementary immunization activities, to determine the community's immunity levels and risk of outbreak propagation.
  • - Findings from her studies emphasize the critical need for effective outbreak response strategies, including rapid investigation, sequence analysis of the poliovirus, and public health initiatives to maintain polio-free status and prevent future outbreaks in regions previously declared free of the disease.