[Design of airborne dual channel ultraviolet-visible imaging spectrometer with large field of view, wide spectrum, and high resolution].

The ultraviolet-visible (UV-Vis 200-500 nm) imaging spectrometer is an important part of space remote sensing. Based on special requirements and practical application of the airborne UV-VIS spectrometer, a kind of scanning imaging spectrometer using area array CCD is proposed, which can meet the application requirements of large field of view, wide spectrum and high resolution. It overcomes low spatial resolution of traditional line array CCD scanning imaging spectrometer, and limited field of view of the pushbroom imaging spectrometer.

[Promoting of angiogenesis and osteogenesis in radial critical bone defect regions of rabbits with nano-hydroxyapatite/collagen/PLA scaffolds plus endothelial progenitor cells].

Objective: To explore the roles of nano-hydroxyapatite/collagen/PLA (nHAC/PLA) plus endothelial progenitor cells (EPCs) in repairing segmental bone defects of rabbit radius and enhancing angiogenesis and new bone formation.

Methods: EPCs isolated from New Zealand white rabbit bone marrow were cultured, identified and seeded into nHAC/PLA scaffolds. And the growth of EPCs in scaffolds was observed under scanning electron microscopy (SEM).

[Needs on information related to influenza pandemic by the public].

Objective: To understand the information needs on human infection with avian influenza (H5N1), A (H1N1) and influenza pandemic in different time periods and create well-targeted messages by the public, so as to develop communication with the public effectively when human infection with avian influenza (H5N1), A (H1N1) and influenza pandemic occur.

Methods: Data were collected through questionnaire over telephone calls. The questionnaire was self-designed, revised after pilot testing.

[Risk assessment of H5N1 human infection after an outbreak of avian influenza in water fowl].

Objective: To evaluate the risk of human infection after the outbreak of avian influenza H5N1 in animals, and probe the possibility for virus transmission.

Methods: By means of field epidemiological study, molecular epidemiology, serology and emergency surveillance, persons who had ever closely contacted with sick or dead poultry were observed. While, the RT-PCR and gene sequencing method were used to detect H5 nucleic acid from environmental swabs from 4 epidemic spots, and hemagglutination inhibition assay was also used to detect H5 antibody.

Germline splicing mutations of CDKN2A predispose to melanoma.

Coding mutations of the CDKN2A gene on chromosome 9p21 cosegregate with 25-60% of familial melanoma cases, but there remains a number of 9p21-linked kindreds that lack germline coding mutations of CDKN2A. We sequenced CDKN2A exons 1alpha, 2, 3, and the adjacent intronic regions in 167 melanoma-prone families (at least two affected first-degree relatives), and detected four splice site variations, three of which cosegregate with the disease. RT-PCR experiments verified that these three variants, including an AGgt to ATgt mutation that demonstrates a founder effect, do affect splicing.