Publications by authors named "Ai-Yun Jiang"

Objective: To systematically evaluate the impact of manual soft tissue therapy (MSTT) on the degree of pain in patients with chronic neck pain (CNP).

Methods: Trials included in the meta-analysis were identified by searching 5 English databases, including the PubMed, Embase, Cochrane Library, Web of Science and U.S.

View Article and Find Full Text PDF

Objectives/hypothesis: To investigate the predictive capability of pepsin level in the laryngeal mucosa to the therapeutic effect of proton-pump inhibitors in patients with suspected laryngopharyngeal reflux (LPR), so as to verify whether it can be referred to as a biomarker of LPR.

Study Design: Prospective case study.

Methods: Sixty patients with clinical empiric LPR were enrolled, with an reflux symptom index (RSI) ≥ 13 and an reflux finding score (RFS) > 7 as screening criteria.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated the effects of human induced pluripotent stem cells-derived mesenchymal stem cells (iPSC-MSCs) on neutrophilic airway inflammation, particularly in cases resistant to steroid treatment.
  • Researchers used a mouse model with induced Type 17 helper T cells (Th17) to evaluate how iPSC-MSCs impacted inflammation and related immune responses.
  • Results showed that iPSC-MSCs significantly reduced inflammation by decreasing the levels of Th17 cells and related cytokines, indicating potential for treating asthma patients who don't respond to steroids.
View Article and Find Full Text PDF

Toxocara canis is a zoonotic parasite with worldwide distribution. ATP-binding cassette (ABC) transporters are integral membrane proteins which involve in a range of biological processes in various organisms. In present study, the full-length coding sequence of abcg-5 gene of T.

View Article and Find Full Text PDF

Background: Nowadays, social media tools such as short message service, Twitter, video, and web-based systems are more and more used in clinical follow-up, making clinical follow-up much more time- and cost-effective than ever before. However, as the most popular social media in China, little is known about the utility of smartphone WeChat application in follow-up. In this study, we aimed to investigate the feasibility and superiority of WeChat application in clinical follow-up.

View Article and Find Full Text PDF

Objective: The therapeutic effect of middle frontal horizontal partial laryngectomy (MFHPL) in treating stage T1b squamous cell carcinoma of the glottic larynx involving anterior vocal commissure (AVC) was compared with that of the anterior frontolateral vertical partial laryngectomy (AFVPL). The feasibility and practical significance of MFHPL in clinical application was discussed in the present study.

Methods: From January 1996 to January 2010, a total of 65 patients diagnosed with stage T1bN0M0 glottic laryngeal cancer were treated with MFHPL or AFVPL.

View Article and Find Full Text PDF

Background: The clinical efficiency and functional outcomes of supracricoid partial laryngectomy (SCPL) with cricothyroidopexy (CTP) were compared with those of the traditional SCPL with cricohyoidoepiglottopexy (CHEP) in treating laryngeal squamous carcinoma involving anterior vocal commissure (AVC).

Methods: From January 2000 to June 2009, 50 patients diagnosed with early- or intermediate-stage (T1b-T3 classification) glottic cancer involving AVC were treated with SCPL-CHEP or SCPL-CTP. Postoperative complications, local recurrence, survival rate, and speech performance were compared between these 2 surgical procedures.

View Article and Find Full Text PDF

This study attempted to explore suitable anesthetic methods used for removal of tracheobronchial foreign body (FB) via self-retaining laryngoscopy and Hopkins telescopy in children. 92 cases had undergone FB removal via self-retaining laryngoscopy and Hopkins telescopy or rigid bronchoscopy in our hospital since 2006, of which 56 cases were under intravenous anesthesia and endotracheal intubation with muscle relaxation (IAEI with MR), and the other 36 cases were under intravenous anesthesia with spontaneous breathing (IASB). Operative parameters and intraoperative vital signs were analyzed.

View Article and Find Full Text PDF

Background And Aim: Little is known about the difference between patients of chronic laryngitis with and without troublesome reflux symptoms. The aim of this study was to compare the clinical characteristics and response to acid suppression between patients of chronic laryngitis with and without troublesome reflux symptoms.

Methods: Consecutive patients with chronic laryngitis were enrolled.

View Article and Find Full Text PDF

Objective: To define the normative data of gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) in healthy Chinese volunteers.

Methods: Healthy volunteers without gastrointestinal and throat disease and symptoms were enrolled and underwent 24-hour impedance-pH monitoring.

Results: A total of 37 healthy volunteers completed all the tests (female 54.

View Article and Find Full Text PDF

Objective: To assess the effect of small interfering RNA (siRNA)-mediated gene silencing of DJ-1 on the proliferation of human laryngeal carcinoma cell line Hep-2.

Methods: Three siRNA sequences specific to DJ-1 gene were synthesized according to GenBank. Human laryngeal carcinoma cell line Hep-2 was cultured and divided into 4 groups: non-specific group (siRNA control) and 3 RNAi groups, transfected with specific DJ-1 siRNA (siRNA1, siRNA2, siRNA3).

View Article and Find Full Text PDF

Objective: To investigate the risk factors causing tracheal stenosis after tracheotomy for mechanical ventilation.

Methods: A retrospective study was carried out to review the clinical data of 560 patients who had been tracheotomy for mechanical ventilation in the First Affiliated Hospital of Sun Yat-sen University from 1990 to 2006. The clinical relevant factors causing tracheal stenosis included age, sex, preoperative intubation, preoperative intubation time, postoperative mechanical ventilation duration, airway infection, multiple changes of intubation tube, cricothyroidotomy, previous tracheotomy, gastroesophageal reflux, diabetes, etc.

View Article and Find Full Text PDF

Objective: To investigate the clinical relevant factors causing laryngeal stenosis after partial laryngectomy.

Methods: A retrospective study was carried out to review the history clinical data from 138 patients of partial laryngectomy in the First Affiliated Hospital of Sun Yat-Sen University between January 1994 to October 2004. The clinical relevant factors causing laryngeal stenosis were included as follows: age, sex, TNM stage, tumor site, extension of thyroid cartilage defect, extension of larynx parenchyma defect, reconstruction method, laryngeal dilator, duration of using antibiotics, postoperative radiotherapy, lung infection, gastroesophageal reflux, diabetes.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to develop and assess a questionnaire measuring quality of life specifically for patients who have undergone laryngectomy for laryngeal cancer.
  • It involved 81 patients who had either partial or total laryngectomy, with analysis focusing on the feasibility, reliability, and validity of the questionnaire.
  • Results showed that the questionnaire is reliable and valid, with significant differences in quality of life scores between the two groups of patients, and identified seven influencing factors affecting post-laryngectomy quality of life.
View Article and Find Full Text PDF