Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.

Non-small-cell lung cancer (NSCLC), a common malignant tumor, requires deeper pathogenesis investigation. Autophagy is an evolutionarily conserved lysosomal degradation process that is frequently blocked during cancer progression. It is an urgent need to determine the novel autophagy-associated regulators in NSCLC.

Sterically demanding Csp(-substitution)-Csp(tertiary) bond formation carboxylate-directed Mizoroki-Heck reaction under extra-ligand-free conditions.

Construction of the sterically demanding Csp(S)-Csp(T) bond was achieved by carrying out the Pd-catalyzed carboxylate-directed Mizoroki-Heck reaction under extra-ligand-free aqueous conditions. The cooperative role of the presence of water with the absence of phosphine ligand was proposed to accelerate the migratory insertion process considerably, delivering a broad substrate scope.

Effects of electroacupuncture therapy for depression: Study protocol for a multicentered, randomized controlled trial.

Introduction: As a major public health problem, depression has a negative impact on individuals and society. The aim of this well-designed trial is to evaluate the efficacy and safety of electroacupuncture (EA) treatment for depression.

Methods/design: A 3-arm parallel, nonblinded, randomized controlled trial will be performed in 4 hospitals (centers).

Thermal Effects of Acupuncture by the Infrared Thermography Test in Patients With Tinnitus.

Previous studies have confirmed the efficacy of acupuncture treatment for tinnitus. However, no relevant studies of the exact mechanism of acupuncture efficacy on tinnitus have been published. Enrolled participants with left-sided tinnitus received acupuncture treatment at TE3 and TE5.