Publications by authors named "Ai-Tien Nguyen"
Scurvy is now considered to be a rare disease in European countries, even among children, but it still exists. We report the case of an 18-month-old boy who was initially hospitalized for a walking disorder and ultimately diagnosed with scurvy. Radiographs were compatible with rickets, but biological analysis ruled out this diagnosis.
View Article and Find Full Text PDFBackground: Rituximab (RTX) resistance or early B-cells repopulation were observed in children but only few publications reported the use of Obinutuzumab and no recommendations were made concerning the dosage for children.
Methods: This study was a single-center retrospective cohort study of all the children followed-up in the Pediatric Neurology Department of Necker-Enfants malades Hospital in Paris, France, and treated with obinutuzumab, between November 1, 2019, and November 1, 2021.
Results: A total of eight children (three females, median age 4.
Article Synopsis
- Paediatric granulomatous uveitis (PGU) is a rare eye condition in kids that can cause serious problems with vision if not diagnosed early.
- The study looked at 50 young patients to understand the causes, treatments, and outcomes related to this condition.
- Most cases were either "idiopathic" (no known cause) or caused by sarcoidosis, and many kids experienced complications, so doctors often used treatments like corticosteroids and methotrexate.
Diagnosis and Management of Non-Infectious Uveitis in Pediatric Patients.
Paediatr Drugs
January 2024
Uveitis in children accounts for 5-10% of all cases. The causes vary considerably. Classically, uveitis is distinguished according to its infectious or inflammatory origin and whether it is part of a systemic disease or represents an isolated ocular disease.
View Article and Find Full Text PDFBackground: RTX is used off-label in several neurological inflammatory diseases in adults children patients. We conducted a study to assess indications and safety of rituximab (RTX) for children and to identify risk factors for early B-cell repopulation.
Methods: A single-center retrospective study of children treated with RTX for a neurological disease between May 31, 2010, and May 31, 2020, was performed.