Palladium-Catalyzed Asymmetric -1,5-Addition with Oximes via Hydroximation of Unsaturated Esters.

Different from electronically matched 1,4- and 1,6-additions, herein, we disclose an electronically mismatched 1,5-conjugate addition process with oximes as the nucleophiles. By this design, the oxime moieties are readily introduced to the γ-position of the electron-deficient substrates in good yields, excellent regioselectivities, and high enantioselectivities. The corresponding allyl oximes are also conveniently transformed into a series of valuable enantioenriched skeletons.

Catalytic Asymmetric Hydroalkoxylation and Formal Hydration and Hydroaminoxylation of Conjugated Dienes.

The straightforward construction of stereogenic centers bearing unprotected functional groups, as in nature, has been a persistent pursuit in synthetic chemistry. Abundant applications of free enantioenriched allyl alcohol and allyl hydroxylamine motifs have made the asymmetric hydration and hydroaminoxylation of conjugated dienes from water and hydroxylamine, respectively, intriguing and efficient routes that have, however, been unachievable thus far. A fundamental challenge is the failure to realize transition-metal-catalyzed enantioselective C-O bond constructions via hydrofunctionalization of conjugated dienes.

[Effect of high-temperature phase change material on the performance of infrared decoy].

The impact of the high-temperature phase change material on conventional infrared decoy's combustion performance and infrared radiation characteristics was studied. The selected high-temperature phase change materials did not reduce infrared radiation in the 3-5 microm or 8-14 microm band of infrared decoy, while extended the burning time, and reduced the burning rate of the grain, thus prolonged the effective interference time of IR decoy. The results show the phase change material is effective infrared decoy functional additives.

[Clinicopathologic and immunophenotypic analysis of myeloid sarcoma].

Objective: To study the clinicopathologic features of myeloid sarcoma and to evaluate the role of immunohistochemical study in diagnosis of this entity.

Methods: Eighty-two cases of myeloid sarcoma were retrieved from the archives of Department of Pathology, West China Hospital of Sichuan University during the period from January, 1990 to February, 2005. The morphologic features were reviewed and classified according to the 2001 WHO classification for hematopoietic and lymphoid tissue tumors.