Publications by authors named "Ai-Jing Ma"
Article Synopsis
- The study focused on the genetic diversity of Mycobacterium tuberculosis (MTB) in a remote mountainous region of southwest China, looking specifically at the Beijing family strains and their association with drug resistance.
- Researchers analyzed 331 MTB strains using SNP and VNTR genotyping, finding that 55.29% belonged to the Beijing family, with 60.66% of those being modern strains.
- Results indicated a significant prevalence of multi-drug resistant tuberculosis (MDR-TB) within the Beijing lineage, along with certain drug resistances, while genetic clustering was not linked to drug resistance, demonstrating the complex nature of MTB in this region.
We have devised a novel amplification strategy based on isothermal strand-displacement polymerization reaction, which was termed multiple cross displacement amplification (MCDA). The approach employed a set of ten specially designed primers spanning ten distinct regions of target sequence and was preceded at a constant temperature (61-65 °C). At the assay temperature, the double-stranded DNAs were at dynamic reaction environment of primer-template hybrid, thus the high concentration of primers annealed to the template strands without a denaturing step to initiate the synthesis.
View Article and Find Full Text PDF[Relationship between renal apparent diffusion coefficient and renal interstitial fibrosis: preliminary study].
Sichuan Da Xue Xue Bao Yi Xue Ban
November 2008
Objective: To explore the relationship between renal ADCs (apparent diffusion coefficient values) and renal interstitial fibrosis (RIF) grades.
Methods: Twenty four patients with chronic renal diseases and 48 healthy volunteers (control group) were examined with SS-EPI DWI at 3. OT MR.