Publications by authors named "Ai-Hui Feng"

Introduction: Patients with early non-small-cell lung cancer (NSCLC) have a relatively long survival time after stereotactic body radiation therapy (SBRT). Predicting radiation-induced pneumonia (RP) has important clinical and social implications for improving the quality of life of such patients. This study developed an RP prediction model by using 3-dimensional (3D) dosiomic features.

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Article Synopsis
  • The study found that focusing on specific parts of the heart is better for predicting heart problems than just looking at the overall heart dose.
  • They created two treatment plans for twenty patients, one regular and one that tries not to damage important heart areas while still treating the main problem.
  • The special plan was successful in reducing harm to key heart parts and also lowered the risks of serious heart diseases compared to the regular plan.
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Objectives: This study attempts to explore a novel peripheral lung stereotactic body radiotherapy (SBRT) planning technique that can balance the pros and cons of three-dimensional conformal radiotherapy (CRT) and intensity-modulated radiation therapy (IMRT) / volumetric modulated arc therapy (VMAT).

Methods: Treatment plans were retrospectively designed based on CRT, IMRT, VMAT, and the proposed CRT-IMRT-combined (Co-CRIM) techniques using Pinnacle treatment planning system (TPS) for 20 peripheral lung cancer patients. Co-CRIM used an inverse optimization algorithm available in Pinnacle TPS.

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Background: Functional planning based merely on 4DCT ventilation imaging has limitations. In this study, we proposed a radiotherapy planning strategy based on 4DCT ventilation imaging and CT density characteristics.

Materials And Methods: For 20 stage III non-small-cell lung cancer (NSCLC) patients, clinical plans and lung-avoidance plans were generated.

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Objectives: This study performed dosimetry studies and secondary cancer risk assessments on using electronic portal imaging device (EPID) and cone beam computed tomography (CBCT) as image guided tools for the early lung cancer patients treated with SBRT.

Methods: The imaging doses from MV-EPID and kV-CBCT of the Edge accelerator were retrospectively added to sixty-one SBRT treatment plans of early lung cancer patients. The MV-EPID imaging dose (6MV Photon beam) was calculated in Pinnacle TPS, and the kV-CBCT imaging dose was simulated and calculated by modeling of the kV energy beam in TPS using Pinnacle automatic modeling program.

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Introduction: Stereotactic body radiotherapy (SBRT) currently adopts non-discriminative prescription regimen. This study attempts to investigate an individualized fraction regimen (IFR) method for SBRT patients with non-small cell lung cancer (NSCLC) based on Uncomplicated and Cancer-free Control Probability (UCFCP).

Methods: Twenty patients with NSCLC were retrospectively prescribed with 40 regimens, ranging from 8Gy×5f to 12Gy×5f in step of 0.

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Article Synopsis
  • - The study investigates how different types of positioning errors in multi-leaf collimators (MLCs) affect the dosage delivered during stereotactic body radiotherapy (SBRT) for patients with early-stage lung cancer.
  • - Three types of MLC errors were simulated: random errors, systematic shifts (left or right), and opposite directional movements of MLC banks; dosimetric parameters and dose sensitivities were then calculated.
  • - Results showed that the dose sensitivities for MLC errors were significantly impacted by whether or not the MU (monitor units) were weighted, highlighting that larger patient volumes reduced dosage sensitivity, especially in automatic plans compared to manually optimized plans.
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