Publications by authors named "Ai-Hui Fan"
The aim of this study was to investigate the effect of lncRNA KCNQ1OT1 on HCC and to explore the possible underlying mechanisms. The expression levels of KCNQ1OT1, miR-149 and S1PR1 were detected by qRT-PCR assay. A dual luciferase reporter assay was used to detect the interaction between KCNQ1OT1 and miR-149, as well as miR-149 and S1PR1.
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- The study investigated the effects of the Rho-kinase inhibitor fasudil (HA-1077) on the migration and vessel formation capabilities of endothelial cells derived from rat bone marrow stem cells.
- Mesenchymal stem cells were isolated, cultured, and differentiated into endothelial cells, which were confirmed through specific markers and functional tests.
- Results showed that HA-1077, especially in combination with VEGF, significantly enhanced cell migration and the formation of capillary-like structures, indicating its potential in promoting vasculogenesis.