Publications by authors named "Ai-Hong Wan"

Background: Previous research has highlighted correlations between blood cell counts and chronic liver disease. Nonetheless, the causal relationships remain unknown.

Aim: To evaluate the causal effect of blood cell traits on liver enzymes and nonalcoholic fatty liver disease (NAFLD) risk.

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Article Synopsis
  • The study evaluated the effectiveness of using ultrasound (US) and microbubbles to deliver CD151 in treating myocardial infarction (MI) in rabbits.
  • The experimental design included five groups of MI rabbits treated with different combinations of CD151 and ultrasound conditions to evaluate changes in CD151 expression and heart function after treatment.
  • Results showed that CD151 delivery improved heart function and increased vessel density in the heart, suggesting that US microbubbles can enhance the therapeutic effects of CD151 for myocardial infarction.
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Continued chemical investigation on the fruits of Aesculus pavia L. resulted in theisolation and identification of two new oleanolic acid saponins, namely vaccaroside A (1) andvaccaroside B (2). The isolated furostanol saponins were evaluated for cytotoxic activity againsthuman normal amniotic and human lung carcinoma cell lines using neutral red and MTT assays.

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Constituents of the fruits of Rubus corchorifolius were investigated. A new compound, namely rubusin A (1), along with three known compounds, was isolated and characterized. Among them, the new compound exhibited significant activity against kidney deficiency, and quercetin and kaempferol were isolated from the fruits of R.

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